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C1DQA1 (C1DQA1_AZOVD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL ACO77553.1
Ordered Locus Names:Avin_13270 EMBL ACO77553.1
OrganismAzotobacter vinelandii (strain DJ / ATCC BAA-1303) [Complete proteome] [HAMAP] EMBL ACO77553.1
Taxonomic identifier322710 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain113 – 308196ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding139 – 19456ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2621Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2751Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C1DQA1 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: FDA64086D7638F1B

FASTA31533,683
        10         20         30         40         50         60 
MNHALKSTLA PQAFGRVAVL FGGKSAERAV SLKSGQAVLE ALQSAGVDAF GIDVGDDLLE 

        70         80         90        100        110        120 
RLGRERIDRA FIVLHGRGGE DGSMQGLLEC VGIPYTGSGV LASALAMDKL RTKQVWQSLG 

       130        140        150        160        170        180 
LPTPRHAVPT SESDCRAAAR DLGFPLIVKP AHEGSSIGMA KVNDIDELIA AWLSARSHDP 

       190        200        210        220        230        240 
QVLVEQWIQG PEFTVALLRG QVLPPIGLGT PHSFYDYDAK YLASDTQYRI PCGLDSSKEE 

       250        260        270        280        290        300 
ELKALCARAC EAVGVQGWAR VDVMQDAEGR FWLLEVNTVP GMTDHSLVPM AARAAGLDFQ 

       310 
QLVLAVLADS VEARG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001157 Genomic DNA. Translation: ACO77553.1.
RefSeqYP_002798528.1. NC_012560.1.

3D structure databases

ProteinModelPortalC1DQA1.
SMRC1DQA1. Positions 15-307.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING322710.Avin_13270.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO77553; ACO77553; Avin_13270.
GeneID7760269.
KEGGavn:Avin_13270.
PATRIC21028933. VBIAzoVin72790_1255.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAANDTQYR.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycAVIN322710:GJ0M-1327-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1DQA1_AZOVD
AccessionPrimary (citable) accession number: C1DQA1
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: June 11, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)