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C1DN43

- C1DN43_AZOVD

UniProt

C1DN43 - C1DN43_AZOVD

Protein

Cytochrome c biogenesis ATP-binding export protein CcmA

Gene

ccmA

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.UniRule annotationSAAS annotation

    Catalytic activityi

    ATP + H2O + heme(In) = ADP + phosphate + heme(Out).UniRule annotationSAAS annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi38 – 458ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. heme-transporting ATPase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cytochrome complex assembly Source: UniProtKB-KW

    Keywords - Molecular functioni

    HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Cytochrome c-type biogenesisUniRule annotationSAAS annotation, TransportUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotationImported, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciAVIN322710:GJ0M-3044-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c biogenesis ATP-binding export protein CcmAUniRule annotation (EC:3.6.3.41UniRule annotation)
    Alternative name(s):
    Heme exporter protein AUniRule annotation
    Gene namesi
    Name:ccmAUniRule annotationImported
    Ordered Locus Names:Avin_30450Imported
    OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
    Taxonomic identifieri322710 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
    ProteomesiUP000002424: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP
    2. outer membrane-bounded periplasmic space Source: InterPro

    Keywords - Cellular componenti

    Cell inner membraneUniRule annotation, Cell membrane, Membrane

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).UniRule annotation

    Protein-protein interaction databases

    STRINGi322710.Avin_30450.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 211206ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation
    Contains ABC transporter domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG4133.
    KOiK02193.
    OMAiNLAWLCA.
    OrthoDBiEOG6SNDS1.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR005895. ABC_transptr_haem_export_CcmA.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR01189. ccmA. 1 hit.
    PROSITEiPS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51243. CCMA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C1DN43-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSPFLEAMA LACERDWRVL FERLDLALAP GDMLQVVGPN GSGKTSLLRL    50
    LAGLMQPTAG EVRLRGRGLR GQRAELARNL LWIGHAPGIK GLLSAEENLA 100
    WLCALHRPLG REAIWAALAA VGLRGFEDVP CHSLSAGQQR RVALARLHLE 150
    APPLWILDEP FTALDRQGVA QLERHLRAHC ERGGMVVLTT HHSLEVRPAT 200
    YRELDLERHA A 211
    Length:211
    Mass (Da):23,266
    Last modified:May 26, 2009 - v1
    Checksum:iF1F88A1682AEF11F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO79210.1.
    RefSeqiYP_002800185.1. NC_012560.1.

    Genome annotation databases

    EnsemblBacteriaiACO79210; ACO79210; Avin_30450.
    GeneIDi7761945.
    KEGGiavn:Avin_30450.
    PATRICi21032238. VBIAzoVin72790_2876.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO79210.1 .
    RefSeqi YP_002800185.1. NC_012560.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 322710.Avin_30450.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO79210 ; ACO79210 ; Avin_30450 .
    GeneIDi 7761945.
    KEGGi avn:Avin_30450.
    PATRICi 21032238. VBIAzoVin72790_2876.

    Phylogenomic databases

    eggNOGi COG4133.
    KOi K02193.
    OMAi NLAWLCA.
    OrthoDBi EOG6SNDS1.

    Enzyme and pathway databases

    BioCyci AVIN322710:GJ0M-3044-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR005895. ABC_transptr_haem_export_CcmA.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR01189. ccmA. 1 hit.
    PROSITEi PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51243. CCMA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DJ / ATCC BAA-1303Imported.

    Entry informationi

    Entry nameiC1DN43_AZOVD
    AccessioniPrimary (citable) accession number: C1DN43
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 26, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3