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Protein

Cytochrome c biogenesis ATP-binding export protein CcmA

Gene

ccmA

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.UniRule annotationSAAS annotation

Catalytic activityi

ATP + H2O + heme(In) = ADP + phosphate + heme(Out).UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi38 – 458ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Cytochrome c-type biogenesisUniRule annotationSAAS annotation, TransportUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-3044-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c biogenesis ATP-binding export protein CcmAUniRule annotation (EC:3.6.3.41UniRule annotation)
Alternative name(s):
Heme exporter protein AUniRule annotation
Gene namesi
Name:ccmAUniRule annotationImported
Ordered Locus Names:Avin_30450Imported
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).UniRule annotation

Protein-protein interaction databases

STRINGi322710.Avin_30450.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 211206ABC transporterUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. [View classification]UniRule annotation
Contains 1 ABC transporter domain.UniRule annotation
Contains ABC transporter domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG4133.
KOiK02193.
OMAiIVIITSH.
OrthoDBiEOG6SNDS1.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR005895. ABC_transptr_haem_export_CcmA.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24220:SF407. PTHR24220:SF407. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01189. ccmA. 1 hit.
PROSITEiPS50893. ABC_TRANSPORTER_2. 1 hit.
PS51243. CCMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1DN43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSPFLEAMA LACERDWRVL FERLDLALAP GDMLQVVGPN GSGKTSLLRL
60 70 80 90 100
LAGLMQPTAG EVRLRGRGLR GQRAELARNL LWIGHAPGIK GLLSAEENLA
110 120 130 140 150
WLCALHRPLG REAIWAALAA VGLRGFEDVP CHSLSAGQQR RVALARLHLE
160 170 180 190 200
APPLWILDEP FTALDRQGVA QLERHLRAHC ERGGMVVLTT HHSLEVRPAT
210
YRELDLERHA A
Length:211
Mass (Da):23,266
Last modified:May 26, 2009 - v1
Checksum:iF1F88A1682AEF11F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO79210.1.
RefSeqiWP_012701596.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO79210; ACO79210; Avin_30450.
KEGGiavn:Avin_30450.
PATRICi21032238. VBIAzoVin72790_2876.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO79210.1.
RefSeqiWP_012701596.1. NC_012560.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi322710.Avin_30450.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO79210; ACO79210; Avin_30450.
KEGGiavn:Avin_30450.
PATRICi21032238. VBIAzoVin72790_2876.

Phylogenomic databases

eggNOGiCOG4133.
KOiK02193.
OMAiIVIITSH.
OrthoDBiEOG6SNDS1.

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-3044-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR005895. ABC_transptr_haem_export_CcmA.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24220:SF407. PTHR24220:SF407. 1 hit.
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01189. ccmA. 1 hit.
PROSITEiPS50893. ABC_TRANSPORTER_2. 1 hit.
PS51243. CCMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJ / ATCC BAA-1303Imported.

Entry informationi

Entry nameiC1DN43_AZOVD
AccessioniPrimary (citable) accession number: C1DN43
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: July 22, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.