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Protein
Submitted name:

Translation elongation factor Tu

Gene

tuf

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi81 – 855GTPUniRule annotation
Nucleotide bindingi136 – 1394GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-612-MONOMER.
AVIN322710:GJ0M-627-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Translation elongation factor TuImported
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:Avin_06090Imported, Avin_06230Imported
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi322710.Avin_06230.

Structurei

3D structure databases

ProteinModelPortaliC1DKJ8.
SMRiC1DKJ8. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIKMTGEL.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1DKJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEKFERNK PHVNVGTIGH VDHGKTTLTA ALTKVCAETW GGAARAFDQI
60 70 80 90 100
DNAPEEKARG ITINTSHVEY DSATRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLSRQVGVPY IVVFLNKADM VDDAELLELV
160 170 180 190 200
EMEVRDLLST YDFPGDDTPI ITGSALMALE GKDDNGIGVS AVRKLVETLD
210 220 230 240 250
SYIPEPVRAV DQPFLMPIED VFSISGRGTV VTGRVERGIV KVGEEVEIVG
260 270 280 290 300
IRPTTKTTCT GVEMFRKLLD EGRAGENIGA LLRGTKREDV ERGQVLAKPG
310 320 330 340 350
TIKPHTKFEA EVYVLSKEEG GRHTPFFKGY RPQFYFRTTD VTGNVELPEG
360 370 380 390
VEMVMPGDNI KMTVTLIAPI AMEDGLRFAI REGGRTVGAG VVAKIIE
Length:397
Mass (Da):43,235
Last modified:May 26, 2009 - v1
Checksum:i1D0ADBDF70547A18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO76861.1.
CP001157 Genomic DNA. Translation: ACO76874.1.
RefSeqiYP_002797836.1. NC_012560.1.
YP_002797849.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO76861; ACO76861; Avin_06090.
ACO76874; ACO76874; Avin_06230.
KEGGiavn:Avin_06090.
avn:Avin_06230.
PATRICi21027543. VBIAzoVin72790_0567.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO76861.1.
CP001157 Genomic DNA. Translation: ACO76874.1.
RefSeqiYP_002797836.1. NC_012560.1.
YP_002797849.1. NC_012560.1.

3D structure databases

ProteinModelPortaliC1DKJ8.
SMRiC1DKJ8. Positions 2-396.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi322710.Avin_06230.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO76861; ACO76861; Avin_06090.
ACO76874; ACO76874; Avin_06230.
KEGGiavn:Avin_06090.
avn:Avin_06230.
PATRICi21027543. VBIAzoVin72790_0567.

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiIKMTGEL.
OrthoDBiEOG6R5C6X.

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-612-MONOMER.
AVIN322710:GJ0M-627-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJImported and DJ / ATCC BAA-1303Imported.

Entry informationi

Entry nameiC1DKJ8_AZOVD
AccessioniPrimary (citable) accession number: C1DKJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: April 1, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.