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C1DJZ5

- C1DJZ5_AZOVD

UniProt

C1DJZ5 - C1DJZ5_AZOVD

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Protein

Alanine racemase

Gene

alr

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei33 – 331Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei129 – 1291SubstrateUniRule annotation
Active sitei258 – 2581Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei306 – 3061Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-4797-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:Avin_47960Imported
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei33 – 331N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi322710.Avin_47960.

Structurei

3D structure databases

ProteinModelPortaliC1DJZ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031446.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1DJZ5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPARALIDL AALRHNYRLA RELGGARALA VVKADAYGHG AVRCARALEA
60 70 80 90 100
EADGFAVACI EEALELREAG IAAPILLLEG FFESAELEPI QRHDLWCVVH
110 120 130 140 150
SPWQLEAIER TALTRPLTCW LKLDSGMHRV GFAPADYRAA HARLMASGKV
160 170 180 190 200
ARIVAMSHFA RADELDCPRV AEQLAQFETA TAGLVAEFSL RNSPALLGWP
210 220 230 240 250
QFFRHGHGDE WLRPGIMLYG ATPFERYQEQ AAQLRPVMTL ESRIIGVREL
260 270 280 290 300
PAGEPVGYGA RFVASRPTRV GVVAMGYADG YPRHAPNGTP VAVDGRPAQL
310 320 330 340 350
IGRVSMDMLT VDLTDLPQAG LGSRVELWGA QVPASEVAAA AGTIAYQLFC
360
NVRRVARSWL D
Length:361
Mass (Da):39,335
Last modified:May 26, 2009 - v1
Checksum:iF51D292FE35F1FBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO80900.1.
RefSeqiYP_002801875.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO80900; ACO80900; Avin_47960.
GeneIDi7763658.
KEGGiavn:Avin_47960.
PATRICi21035635. VBIAzoVin72790_4541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001157 Genomic DNA. Translation: ACO80900.1 .
RefSeqi YP_002801875.1. NC_012560.1.

3D structure databases

ProteinModelPortali C1DJZ5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 322710.Avin_47960.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO80900 ; ACO80900 ; Avin_47960 .
GeneIDi 7763658.
KEGGi avn:Avin_47960.
PATRICi 21035635. VBIAzoVin72790_4541.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031446.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci AVIN322710:GJ0M-4797-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJ / ATCC BAA-1303Imported.

Entry informationi

Entry nameiC1DJZ5_AZOVD
AccessioniPrimary (citable) accession number: C1DJZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: November 26, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3