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C1DHY7 (TRPC_AZOVD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase

Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:Avin_46110
OrganismAzotobacter vinelandii (strain DJ / ATCC BAA-1303) [Complete proteome] [HAMAP]
Taxonomic identifier322710 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP-Rule MF_00134

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP-Rule MF_00134

Sequence similarities

Belongs to the TrpC family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionindole-3-glycerol-phosphate synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Indole-3-glycerol phosphate synthase HAMAP-Rule MF_00134
PRO_1000203197

Sequences

Sequence LengthMass (Da)Tools
C1DHY7 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: E9E6469E13CD2C42

FASTA26628,905
        10         20         30         40         50         60 
MSLPTVLEKI IARKLEEVAE RSARVPLAEV EALARSASAP RGFAEALRAQ VESKEPAVIA 

        70         80         90        100        110        120 
EVKKASPSKG VLREHFVPAE IAKSYEEGGA TCLSVLTDVD FFQGSDAYLQ EARAACGLPV 

       130        140        150        160        170        180 
IRKDFLIDPY QVVEARALGA DCVLLIVAAL GDAQMLELAA TAKEVGLDVL VEVHDGTELE 

       190        200        210        220        230        240 
RALQLETPLI GINNRNLHTF EVSLETTLDL LPKVPRERLV VTESGILNRA DVELMEVSGV 

       250        260 
YAFLVGEAFM RAEKPGAELR RLFFPN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001157 Genomic DNA. Translation: ACO80720.1.
RefSeqYP_002801695.1. NC_012560.1.

3D structure databases

ProteinModelPortalC1DHY7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING322710.Avin_46110.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO80720; ACO80720; Avin_46110.
GeneID7763476.
KEGGavn:Avin_46110.
PATRIC21035261. VBIAzoVin72790_4356.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0134.
HOGENOMHOG000230462.
KOK01609.
OMARKDFMFE.
OrthoDBEOG6WT8JX.
ProtClustDBPRK00278.

Enzyme and pathway databases

BioCycAVIN322710:GJ0M-4613-MONOMER.
UniPathwayUPA00035; UER00043.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00134_B. IGPS_B.
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_AZOVD
AccessionPrimary (citable) accession number: C1DHY7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: February 19, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways