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C1DHY7

- TRPC_AZOVD

UniProt

C1DHY7 - TRPC_AZOVD

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Protein
Indole-3-glycerol phosphate synthase
Gene
trpC, Avin_46110
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-4613-MONOMER.
UniPathwayiUPA00035; UER00043.

Names & Taxonomyi

Protein namesi
Recommended name:
Indole-3-glycerol phosphate synthase (EC:4.1.1.48)
Short name:
IGPS
Gene namesi
Name:trpC
Ordered Locus Names:Avin_46110
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266Indole-3-glycerol phosphate synthaseUniRule annotation
PRO_1000203197Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi322710.Avin_46110.

Structurei

3D structure databases

ProteinModelPortaliC1DHY7.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpC family.

Phylogenomic databases

eggNOGiCOG0134.
HOGENOMiHOG000230462.
KOiK01609.
OMAiRKDFMFE.
OrthoDBiEOG6WT8JX.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00134_B. IGPS_B.
InterProiIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
PROSITEiPS00614. IGPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1DHY7-1 [UniParc]FASTAAdd to Basket

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MSLPTVLEKI IARKLEEVAE RSARVPLAEV EALARSASAP RGFAEALRAQ    50
VESKEPAVIA EVKKASPSKG VLREHFVPAE IAKSYEEGGA TCLSVLTDVD 100
FFQGSDAYLQ EARAACGLPV IRKDFLIDPY QVVEARALGA DCVLLIVAAL 150
GDAQMLELAA TAKEVGLDVL VEVHDGTELE RALQLETPLI GINNRNLHTF 200
EVSLETTLDL LPKVPRERLV VTESGILNRA DVELMEVSGV YAFLVGEAFM 250
RAEKPGAELR RLFFPN 266
Length:266
Mass (Da):28,905
Last modified:May 26, 2009 - v1
Checksum:iE9E6469E13CD2C42
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO80720.1.
RefSeqiYP_002801695.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO80720; ACO80720; Avin_46110.
GeneIDi7763476.
KEGGiavn:Avin_46110.
PATRICi21035261. VBIAzoVin72790_4356.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO80720.1 .
RefSeqi YP_002801695.1. NC_012560.1.

3D structure databases

ProteinModelPortali C1DHY7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 322710.Avin_46110.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO80720 ; ACO80720 ; Avin_46110 .
GeneIDi 7763476.
KEGGi avn:Avin_46110.
PATRICi 21035261. VBIAzoVin72790_4356.

Phylogenomic databases

eggNOGi COG0134.
HOGENOMi HOG000230462.
KOi K01609.
OMAi RKDFMFE.
OrthoDBi EOG6WT8JX.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00043 .
BioCyci AVIN322710:GJ0M-4613-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00134_B. IGPS_B.
InterProi IPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00218. IGPS. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
PROSITEi PS00614. IGPS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJ / ATCC BAA-1303.

Entry informationi

Entry nameiTRPC_AZOVD
AccessioniPrimary (citable) accession number: C1DHY7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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