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C1DHR7 (SYR_AZOVD) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Avin_45360
OrganismAzotobacter vinelandii (strain DJ / ATCC BAA-1303) [Complete proteome] [HAMAP]
Taxonomic identifier322710 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter

Protein attributes

Sequence length579 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 579579Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000203087

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
C1DHR7 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 9DBDE7A8D89EA240

FASTA57963,998
        10         20         30         40         50         60 
MKDTIRQLIQ QALTRLTDDG VLPAGLTPAI QVENTKDKSH GDFASNIAMM LAKPAGLKPR 

        70         80         90        100        110        120 
QLAEKLVAAL PADASVSKVE IAGPGFLNFF QNSDALARRL EVALADERLG VRKHGDLQRV 

       130        140        150        160        170        180 
VVDLSSPNLA KEMHVGHLRS TIIGDAVARV LEFLGDVVIR QNHVGDWGTQ FGMLLAHLEE 

       190        200        210        220        230        240 
KPASAESELA DLEQFYRAAK KRFDESEAFA DRARELVVRL QAGEPECLRL WQRFNAISLS 

       250        260        270        280        290        300 
HCQEVYERLG VRLTPDDIRG ESAYNDELPG IVQALRDKGL LTESEGAQCV FLDEFRNAEG 

       310        320        330        340        350        360 
NPLPVIVQKA GGGYLYATTD LASMRYRSQV LKADRVLYFV DQRQALHFQM TFAVARRAGF 

       370        380        390        400        410        420 
VRDDTALEHM GFGTMNGADG RPFKTRDGGT VKLIDLLDEA EQRAYALVKG KNPELPEEEL 

       430        440        450        460        470        480 
RHIARAVGIG AVKYADLSKH RTSDYSFNFE LMLSFEGNTA PYLLYAYTRV ASVFRKLGRE 

       490        500        510        520        530        540 
IDEIDGSPAP EAGQELALAA RLAQFGEVLG NVAEKGLPHL LCAYLYDLAG LFSSFYENCP 

       550        560        570 
ILTADTPARQ QSRLLLAALT GRTLRQGLEL LGLEPLERM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001157 Genomic DNA. Translation: ACO80650.1.
RefSeqYP_002801625.1. NC_012560.1.

3D structure databases

ProteinModelPortalC1DHR7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING322710.Avin_45360.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO80650; ACO80650; Avin_45360.
GeneID7763404.
KEGGavn:Avin_45360.
PATRIC21035099. VBIAzoVin72790_4280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycAVIN322710:GJ0M-4534-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_AZOVD
AccessionPrimary (citable) accession number: C1DHR7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: April 16, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries