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C1DHE4

- C1DHE4_AZOVD

UniProt

C1DHE4 - C1DHE4_AZOVD

Protein

Peptidyl-prolyl cis-trans isomerase

Gene

Avin_23510

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    PPIases accelerate the folding of proteins.UniRule annotation
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

    Catalytic activityi

    Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei51 – 511SuccinateImported
    Binding sitei97 – 971SuccinateImported

    GO - Molecular functioni

    1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. protein folding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase, RotamaseUniRule annotation

    Enzyme and pathway databases

    BioCyciAVIN322710:GJ0M-2350-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
    Gene namesi
    Ordered Locus Names:Avin_23510Imported
    OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
    Taxonomic identifieri322710 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
    ProteomesiUP000002424: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi322710.Avin_23510.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3T1UX-ray2.00A2-163[»]
    ProteinModelPortaliC1DHE4.
    SMRiC1DHE4. Positions 1-162.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PPIase cyclophilin-type domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0652.
    HOGENOMiHOG000065978.
    KOiK03768.
    OMAiLHTNHGE.
    OrthoDBiEOG6S26C3.

    Family and domain databases

    Gene3Di2.40.100.10. 1 hit.
    InterProiIPR029000. Cyclophilin-like_dom.
    IPR020892. Cyclophilin-type_PPIase_CS.
    IPR002130. Cyclophilin-type_PPIase_dom.
    [Graphical view]
    PfamiPF00160. Pro_isomerase. 1 hit.
    [Graphical view]
    PRINTSiPR00153. CSAPPISMRASE.
    SUPFAMiSSF50891. SSF50891. 1 hit.
    PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
    PS50072. CSA_PPIASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C1DHE4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKLQTNHGT ITLKLFADKA PETAANFEQY VKDGHYDGTI FHRVIDGFMI    50
    QGGGFEPGMK QKSTRAPIKN EANNGLSNKK YTIAMARTPD PHSASAQFFI 100
    NVKDNAFLDH TAPTAHGWGY AVFGEVVEGT DVVDRIKSVA TGSRAGHGDV 150
    PVDDVIIEKA EIVE 164
    Length:164
    Mass (Da):17,831
    Last modified:May 26, 2009 - v1
    Checksum:iA7C2E78E0943ABC8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO78539.1.
    RefSeqiYP_002799514.1. NC_012560.1.

    Genome annotation databases

    EnsemblBacteriaiACO78539; ACO78539; Avin_23510.
    GeneIDi7761267.
    KEGGiavn:Avin_23510.
    PATRICi21030925. VBIAzoVin72790_2232.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001157 Genomic DNA. Translation: ACO78539.1 .
    RefSeqi YP_002799514.1. NC_012560.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3T1U X-ray 2.00 A 2-163 [» ]
    ProteinModelPortali C1DHE4.
    SMRi C1DHE4. Positions 1-162.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 322710.Avin_23510.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO78539 ; ACO78539 ; Avin_23510 .
    GeneIDi 7761267.
    KEGGi avn:Avin_23510.
    PATRICi 21030925. VBIAzoVin72790_2232.

    Phylogenomic databases

    eggNOGi COG0652.
    HOGENOMi HOG000065978.
    KOi K03768.
    OMAi LHTNHGE.
    OrthoDBi EOG6S26C3.

    Enzyme and pathway databases

    BioCyci AVIN322710:GJ0M-2350-MONOMER.

    Family and domain databases

    Gene3Di 2.40.100.10. 1 hit.
    InterProi IPR029000. Cyclophilin-like_dom.
    IPR020892. Cyclophilin-type_PPIase_CS.
    IPR002130. Cyclophilin-type_PPIase_dom.
    [Graphical view ]
    Pfami PF00160. Pro_isomerase. 1 hit.
    [Graphical view ]
    PRINTSi PR00153. CSAPPISMRASE.
    SUPFAMi SSF50891. SSF50891. 1 hit.
    PROSITEi PS00170. CSA_PPIASE_1. 1 hit.
    PS50072. CSA_PPIASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DJ / ATCC BAA-1303Imported.
    2. "Structure of a bacterial cytoplasmic cyclophilin A in complex with a tetrapeptide."
      Christoforides E., Dimou M., Katinakis P., Bethanis K., Karpusas M.
      Acta Crystallogr. F 68:259-264(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-163 IN COMPLEX WITH SUCCINATE.

    Entry informationi

    Entry nameiC1DHE4_AZOVD
    AccessioniPrimary (citable) accession number: C1DHE4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 26, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3