Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C1DHE4

- C1DHE4_AZOVD

UniProt

C1DHE4 - C1DHE4_AZOVD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptidyl-prolyl cis-trans isomerase

Gene

Avin_23510

Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

PPIases accelerate the folding of proteins.
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei51 – 511SuccinateImported
Binding sitei97 – 971SuccinateImported

GO - Molecular functioni

  1. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, RotamaseUniRule annotation

Enzyme and pathway databases

BioCyciAVIN322710:GJ0M-2350-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Gene namesi
Ordered Locus Names:Avin_23510Imported
OrganismiAzotobacter vinelandii (strain DJ / ATCC BAA-1303)Imported
Taxonomic identifieri322710 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter
ProteomesiUP000002424: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi322710.Avin_23510.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3T1UX-ray2.00A2-163[»]
ProteinModelPortaliC1DHE4.
SMRiC1DHE4. Positions 1-162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclophilin-type PPIase family.UniRule annotation
Contains 1 PPIase cyclophilin-type domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0652.
HOGENOMiHOG000065978.
KOiK03768.
OMAiLHTNHGE.
OrthoDBiEOG6S26C3.

Family and domain databases

Gene3Di2.40.100.10. 1 hit.
InterProiIPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PfamiPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PRINTSiPR00153. CSAPPISMRASE.
SUPFAMiSSF50891. SSF50891. 1 hit.
PROSITEiPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1DHE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIKLQTNHGT ITLKLFADKA PETAANFEQY VKDGHYDGTI FHRVIDGFMI
60 70 80 90 100
QGGGFEPGMK QKSTRAPIKN EANNGLSNKK YTIAMARTPD PHSASAQFFI
110 120 130 140 150
NVKDNAFLDH TAPTAHGWGY AVFGEVVEGT DVVDRIKSVA TGSRAGHGDV
160
PVDDVIIEKA EIVE
Length:164
Mass (Da):17,831
Last modified:May 26, 2009 - v1
Checksum:iA7C2E78E0943ABC8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO78539.1.
RefSeqiYP_002799514.1. NC_012560.1.

Genome annotation databases

EnsemblBacteriaiACO78539; ACO78539; Avin_23510.
GeneIDi7761267.
KEGGiavn:Avin_23510.
PATRICi21030925. VBIAzoVin72790_2232.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001157 Genomic DNA. Translation: ACO78539.1 .
RefSeqi YP_002799514.1. NC_012560.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3T1U X-ray 2.00 A 2-163 [» ]
ProteinModelPortali C1DHE4.
SMRi C1DHE4. Positions 1-162.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 322710.Avin_23510.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO78539 ; ACO78539 ; Avin_23510 .
GeneIDi 7761267.
KEGGi avn:Avin_23510.
PATRICi 21030925. VBIAzoVin72790_2232.

Phylogenomic databases

eggNOGi COG0652.
HOGENOMi HOG000065978.
KOi K03768.
OMAi LHTNHGE.
OrthoDBi EOG6S26C3.

Enzyme and pathway databases

BioCyci AVIN322710:GJ0M-2350-MONOMER.

Family and domain databases

Gene3Di 2.40.100.10. 1 hit.
InterProi IPR029000. Cyclophilin-like_dom.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view ]
Pfami PF00160. Pro_isomerase. 1 hit.
[Graphical view ]
PRINTSi PR00153. CSAPPISMRASE.
SUPFAMi SSF50891. SSF50891. 1 hit.
PROSITEi PS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DJ / ATCC BAA-1303Imported.
  2. "Structure of a bacterial cytoplasmic cyclophilin A in complex with a tetrapeptide."
    Christoforides E., Dimou M., Katinakis P., Bethanis K., Karpusas M.
    Acta Crystallogr. F 68:259-264(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-163 IN COMPLEX WITH SUCCINATE.

Entry informationi

Entry nameiC1DHE4_AZOVD
AccessioniPrimary (citable) accession number: C1DHE4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3