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Protein
Submitted name:

Exonuclease

Gene

LHK_01497

Organism
Laribacter hongkongensis (strain HLHK9)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi102 – 1021MagnesiumCombined sources
Metal bindingi112 – 1121MagnesiumCombined sources
Metal bindingi113 – 1131Magnesium; via carbonyl oxygenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ExonucleaseImported, Hydrolase, Nuclease

Keywords - Ligandi

MagnesiumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciLHON557598:GHO5-1527-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ExonucleaseImported
Gene namesi
Ordered Locus Names:LHK_01497Imported
OrganismiLaribacter hongkongensis (strain HLHK9)Imported
Taxonomic identifieri557598 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeLaribacter
Proteomesi
  • UP000002010 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi557598.LHK_01497.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SYYX-ray1.90A1-203[»]
3SZ4X-ray2.59A1-203[»]
3SZ5X-ray2.80A1-203[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 148142YqaJInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105RMG. Bacteria.
ENOG4111FJH. LUCA.
HOGENOMiHOG000226545.
OMAiAVFMKFR.
OrthoDBiEOG6XSZSV.

Family and domain databases

Gene3Di3.90.320.10. 1 hit.
InterProiIPR011604. Exonuc_phg/RecB_C.
IPR017482. Phage_endonuclease_put.
IPR011335. Restrct_endonuc-II-like.
IPR019080. YqaJ_viral_recombinase.
[Graphical view]
PfamiPF09588. YqaJ. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR03033. phage_rel_nuc. 1 hit.

Sequencei

Sequence statusi: Complete.

C1D7P6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQRTEEWFA ARLGKVTASR VADVMTKTKS GYAASRQNYM AELICQRLTG
60 70 80 90 100
TQEIRFSNAA MQRGTELEPH ARARYIIETG EIVTEVGLID HPTIAGFGAS
110 120 130 140 150
PDGLVGDTGL IEIKCPNTWT HIETIKTGKP KPEYIKQMQT QMACTGRQWC
160 170 180 190 200
DFVSYDDRLP DDMQYFCTRI ERDDALIAEI ETEVSAFLAE LEAEIEYLKR

KAA
Length:203
Mass (Da):22,923
Last modified:May 26, 2009 - v1
Checksum:i8277A2B1701531AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001154 Genomic DNA. Translation: ACO74486.1.
RefSeqiWP_012696972.1. NC_012559.1.

Genome annotation databases

EnsemblBacteriaiACO74486; ACO74486; LHK_01497.
KEGGilhk:LHK_01497.
PATRICi22299981. VBILarHon49832_1385.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001154 Genomic DNA. Translation: ACO74486.1.
RefSeqiWP_012696972.1. NC_012559.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SYYX-ray1.90A1-203[»]
3SZ4X-ray2.59A1-203[»]
3SZ5X-ray2.80A1-203[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi557598.LHK_01497.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO74486; ACO74486; LHK_01497.
KEGGilhk:LHK_01497.
PATRICi22299981. VBILarHon49832_1385.

Phylogenomic databases

eggNOGiENOG4105RMG. Bacteria.
ENOG4111FJH. LUCA.
HOGENOMiHOG000226545.
OMAiAVFMKFR.
OrthoDBiEOG6XSZSV.

Enzyme and pathway databases

BioCyciLHON557598:GHO5-1527-MONOMER.

Family and domain databases

Gene3Di3.90.320.10. 1 hit.
InterProiIPR011604. Exonuc_phg/RecB_C.
IPR017482. Phage_endonuclease_put.
IPR011335. Restrct_endonuc-II-like.
IPR019080. YqaJ_viral_recombinase.
[Graphical view]
PfamiPF09588. YqaJ. 1 hit.
[Graphical view]
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR03033. phage_rel_nuc. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats."
    Woo P.C., Lau S.K., Tse H., Teng J.L., Curreem S.O., Tsang A.K., Fan R.Y., Wong G.K., Huang Y., Loman N.J., Snyder L.A., Cai J.J., Huang J.D., Mak W., Pallen M.J., Lok S., Yuen K.Y.
    PLoS Genet. 5:E1000416-E1000416(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HLHK9Imported.
  2. "Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis."
    Yang W., Chen W.Y., Wang H., Ho J.W., Huang J.D., Woo P.C., Lau S.K., Yuen K.Y., Zhang Q., Zhou W., Bartlam M., Watt R.M., Rao Z.
    Nucleic Acids Res. 39:9803-9819(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.

Entry informationi

Entry nameiC1D7P6_LARHH
AccessioniPrimary (citable) accession number: C1D7P6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: March 16, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.