C1CZ72 (C1CZ72_DEIDV) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetylglutamate/acetylaminoadipate kinase HAMAP MF_00082
EC=2.7.2.- HAMAP MF_00082
EC=2.7.2.8 HAMAP MF_00082

Alternative name(s):
N-acetyl-L-glutamate/N-acetyl-L-aminoadipate 5-phosphotransferase HAMAP MF_00082
NAG kinase HAMAP MF_00082

Gene names

Name:	argB HAMAP MF_00082 EMBL ACO45110.1
Synonyms:	lysZ HAMAP MF_00082
Ordered Locus Names:	Deide_02920

Organism

Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) [Complete proteome] [HAMAP]

Taxonomic identifier

546414 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in both the arginine and lysine biosynthetic pathways By similarity. HAMAP MF_00082
Catalytic activity	ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate. HAMAP MF_00082 ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082 Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 2/5. HAMAP MF_00082
Subcellular location	Cytoplasm By similarity HAMAP MF_00082.
Sequence similarities	Belongs to the acetylglutamate kinase family. HAMAP MF_00082

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00082 Lysine biosynthesis HAMAP MF_00082
Cellular component	Cytoplasm HAMAP MF_00082
Ligand	ATP-binding HAMAP MF_00082 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00082 EMBL ACO45110.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: HAMAP lysine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP acetylglutamate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	44 – 45	2	Substrate binding By similarity HAMAP MF_00082
Sites
	Binding site	66	1	Substrate By similarity HAMAP MF_00082
	Binding site	153	1	Substrate By similarity HAMAP MF_00082
	Site	10	1	Transition state stabilizer By similarity HAMAP MF_00082
	Site	215	1	Transition state stabilizer By similarity HAMAP MF_00082

Sequences

	Sequence		Length	Mass (Da)
	C1CZ72 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: C0564F65A178CCB2	FASTA	255	26,439
	10 20 30 40 50 60 MPYTAGVIVK YGGNAMKSLE LRRAVASEIA AVRRELPVVV VHGGGPVIER ELSARQIPSE 70 80 90 100 110 120 FRGGLRVTSP EAMDVVEMAL CQLNKQLSQD VGQAVGLMGR DCELLRAEVL DPALGRVGRV 130 140 150 160 170 180 TAVNADLLRT LLGAGLTPVV GCIAVGLDGE ALNINADTAA GAVAGALNEG IIFLTDVDGV 190 200 210 220 230 240 YRSFPDPESR ALVLRRAEVE AGISEGWIAG GMIPKVRAAL DALERGAPFA TIASGMHSGV 250 LAAAVRGEAG TRILP

References

[1]

"Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti." de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P., Fernandez B., Vacherie B., Dossat C., Jolivet E., Siguier P., Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W., Armengaud J. PLoS Genet. 5:E1000434-E1000434(2009) [PubMed: 19370165] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VCD115 / DSM 17065 / LMG 22923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001114 Genomic DNA. Translation: ACO45110.1.
RefSeq	YP_002784864.1. NC_012526.1.
3D structure databases
ProteinModelPortal	C1CZ72.
ModBase	Search...
Protein-protein interaction databases
STRING	C1CZ72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7738914.
GenomeReviews	Gene locus Deide_02920 in contig CP001114_GR.
KEGG	ddr:Deide_02920.
PATRIC	21614026. VBIDeiDes121019_0321.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GGCLVDD.
ProtClustDB	CLSK445594.
Family and domain databases
HAMAP	MF_00082_B. ArgB_B. [Tree]
InterPro	IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KO	K00930.
Pfam	PF00696. AA_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000728. NAGK. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit.
TIGRFAMs	TIGR00761. ArgB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1CZ72_DEIDV

Accession

Primary (citable) accession number: C1CZ72

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)