Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei385UniRule annotation1
Active sitei510UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciDDES546414:G1GCG-1970-MONOMER
UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Deide_17080
OrganismiDeinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923)
Taxonomic identifieri546414 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus
Proteomesi
  • UP000002208 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002063611 – 544Glucose-6-phosphate isomeraseAdd BLAST544

Proteomic databases

PaxDbiC1CWW2

Interactioni

Protein-protein interaction databases

STRINGi546414.Deide_17080

Structurei

3D structure databases

SMRiC1CWW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C89 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

C1CWW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAALTETPA WQALQAHFET LHSVHLRDLF AADPGRGERL TAEGAGLYLD
60 70 80 90 100
YSKHRVTDET LDLLVALAHA RGLPERRDAM FGGEKINVTE GRAVLHTALR
110 120 130 140 150
APRGSDVLVD GRNVVPDVHE VLERMAAFAQ QVRSGSWLGH TGKPIRAIVN
160 170 180 190 200
IGIGGSDLGP VMAYEALRHY AQRELTVRFV SNVDGTDLVE KTRDLTAEET
210 220 230 240 250
LFIVSSKTFT TQETMANAQS ARAWLLSALG DEAAVARHFV AVSTNAEAVQ
260 270 280 290 300
KFGIDTANMF EFWDWVGGRY SMDSAIGLSL MLAIGPDGFR ELLSGFHDMD
310 320 330 340 350
EHFRTAPLEA NLPVLMGLLG VWYNNFFGAE TLAVLPYDQY LAYFPAYLQQ
360 370 380 390 400
LDMESNGKHV TLDGQEVTYQ TGPVVWGQPG TNGQHAFYQL IHQGTKLIPC
410 420 430 440 450
DFIAFAQTLN PLPLPGGAPH HDLLMANVFA QTEALAFGKT LEEVLAEGVD
460 470 480 490 500
AALAPHRVFD GNRPTSTLLV DRLTPRTLGA LIALYEHKVF VQGVIWDVNS
510 520 530 540
FDQWGVELGK VLARRIVKEL GADEPELSHD SSTNALIRRY RERR
Length:544
Mass (Da):59,923
Last modified:May 26, 2009 - v1
Checksum:i1B752831A984EEB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001114 Genomic DNA Translation: ACO46679.1
RefSeqiWP_012693801.1, NC_012526.1

Genome annotation databases

EnsemblBacteriaiACO46679; ACO46679; Deide_17080
KEGGiddr:Deide_17080

Similar proteinsi

Entry informationi

Entry nameiG6PI_DEIDV
AccessioniPrimary (citable) accession number: C1CWW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: February 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health