C1CWW2 (G6PI_DEIDV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI

Gene names

Name:	pgi
Ordered Locus Names:	Deide_17080

Organism

Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) [Complete proteome] [HAMAP]

Taxonomic identifier

546414 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	544 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00473 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity HAMAP MF_00473.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 544	544	Glucose-6-phosphate isomerase HAMAP MF_00473		PRO_1000206361
Sites
	Active site	385	1	By similarity
	Active site	510	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	C1CWW2 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 1B752831A984EEB6	FASTA	544	59,923
	10 20 30 40 50 60 MSAALTETPA WQALQAHFET LHSVHLRDLF AADPGRGERL TAEGAGLYLD YSKHRVTDET 70 80 90 100 110 120 LDLLVALAHA RGLPERRDAM FGGEKINVTE GRAVLHTALR APRGSDVLVD GRNVVPDVHE 130 140 150 160 170 180 VLERMAAFAQ QVRSGSWLGH TGKPIRAIVN IGIGGSDLGP VMAYEALRHY AQRELTVRFV 190 200 210 220 230 240 SNVDGTDLVE KTRDLTAEET LFIVSSKTFT TQETMANAQS ARAWLLSALG DEAAVARHFV 250 260 270 280 290 300 AVSTNAEAVQ KFGIDTANMF EFWDWVGGRY SMDSAIGLSL MLAIGPDGFR ELLSGFHDMD 310 320 330 340 350 360 EHFRTAPLEA NLPVLMGLLG VWYNNFFGAE TLAVLPYDQY LAYFPAYLQQ LDMESNGKHV 370 380 390 400 410 420 TLDGQEVTYQ TGPVVWGQPG TNGQHAFYQL IHQGTKLIPC DFIAFAQTLN PLPLPGGAPH 430 440 450 460 470 480 HDLLMANVFA QTEALAFGKT LEEVLAEGVD AALAPHRVFD GNRPTSTLLV DRLTPRTLGA 490 500 510 520 530 540 LIALYEHKVF VQGVIWDVNS FDQWGVELGK VLARRIVKEL GADEPELSHD SSTNALIRRY RERR

References

[1]

"Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti." de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P., Fernandez B., Vacherie B., Dossat C., Jolivet E., Siguier P., Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W., Armengaud J. PLoS Genet. 5:E1000434-E1000434(2009) [PubMed: 19370165] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VCD115 / DSM 17065 / LMG 22923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001114 Genomic DNA. Translation: ACO46679.1.
RefSeq	YP_002786433.1. NC_012526.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1CWW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7737386.
GenomeReviews	Gene locus Deide_17080 in contig CP001114_GR.
KEGG	ddr:Deide_17080.
PATRIC	21617374. VBIDeiDes121019_1965.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NSLPAWT.
ProtClustDB	PRK00179.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR023096. G6P_Isomerase_C. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
Gene3D	G3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
KO	K01810.
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI_DEIDV

Accession

Primary (citable) accession number: C1CWW2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program