C1CWA3 (GLMM_DEIDV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Deide_15140

Organism

Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) [Complete proteome] [HAMAP]

Taxonomic identifier

546414 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › Deinococcus deserti

Protein attributes

Sequence length	442 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 442	442	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_1000215484
Sites
	Active site	103	1	Phosphoserine intermediate By similarity
	Metal binding	103	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	103	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	C1CWA3 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: CEADCDF0536D1C0C	FASTA	442	47,197
	10 20 30 40 50 60 MSERKYFGTD GVRAVAGEFP LTSAWVMSLG AAAGEVLRRV NPHARVVIGK DTRQSGDMLE 70 80 90 100 110 120 AALAAGLTSR GVTVIHVGVL PTPGVSYLTR HLKADAGVVI SASHNPYEDN GIKFFGADGQ 130 140 150 160 170 180 KLSDATELQI EAAIDEVPGF APLTGTAMGS VTNYTEAEHL YTDFLKSHAP DLSGLKIALD 190 200 210 220 230 240 CANGAAYRVA PKVFQAAGAD VFAIYTTPDG RNINRGCGST HMDHLRQIVR EGEYDLGVAF 250 260 270 280 290 300 DGDADRALFV DSRGQVVHGD HMLLLNARAR GEQAVVATIM TNMALEAKLQ DAGIPLERTA 310 320 330 340 350 360 VGDRYVHERL HEKGLSLGGE QSGHVLFLDI SPTGDGVLTA LLTLASMKKL GTTLDALHDD 370 380 390 400 410 420 LVMYPQTLVN VRVQDKKAIA VDQQVQQAVR QAEEQLLGRG RVNLRPSGTE NLIRVMVEGQ 430 440 DAAEIHEVAR VLAGVVEARG QA

References

[1]

"Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti." de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P., Fernandez B., Vacherie B., Dossat C., Jolivet E., Siguier P., Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W., Armengaud J. PLoS Genet. 5:E1000434-E1000434(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VCD115 / DSM 17065 / LMG 22923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001114 Genomic DNA. Translation: ACO46470.1.
RefSeq	YP_002786224.1. NC_012526.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	546414.Deide_15140.
Proteomic databases
PaxDb	C1CWA3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACO46470; ACO46470; Deide_15140.
GeneID	7738150.
KEGG	ddr:Deide_15140.
PATRIC	21616924. VBIDeiDes121019_1741.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK14323.
Enzyme and pathway databases
BioCyc	DDES546414:GHOM-2586-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_DEIDV

Accession

Primary (citable) accession number: C1CWA3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program