C1CV26 (SYN_DEIDV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Asparagine--tRNA ligase
EC=6.1.1.22

Alternative name(s):
Asparaginyl-tRNA synthetase
Short name=AsnRS

Gene names

Name:	asnS
Ordered Locus Names:	Deide_11380

Organism

Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) [Complete proteome] [HAMAP]

Taxonomic identifier

546414 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus

Protein attributes

Sequence length	445 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + L-asparaginyl-tRNA(Asn). HAMAP MF_00534
Subunit structure	Homodimer By similarity. HAMAP MF_00534
Subcellular location	Cytoplasm By similarity HAMAP MF_00534.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asparaginyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW asparagine-tRNA ligase activity Inferred from electronic annotation. Source: EC nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 445	445	Asparagine--tRNA ligase HAMAP MF_00534		PRO_1000211901

Sequences

	Sequence		Length	Mass (Da)
	C1CV26 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 570586EDC6AE506E	FASTA	445	50,937
	10 20 30 40 50 60 MISNIRDLKQ HVGETVTLQA WLTDKSGKGK IQFLKLRDGS GFVQATVFKN DVEEEVFESA 70 80 90 100 110 120 KRLTQEQALT LTGEVRADER APGGVELSVR RLSPISENHA EYPITPKEHG IEFLMDQRHL 130 140 150 160 170 180 WLRHRRPWAI MRIRDCVQRA IVDFFHSEGF VRFDAPFFTP NAAEGTTELF EIDLFGEDKA 190 200 210 220 230 240 YLSQTGQLHA EAGAFAFGKV YTFGPTFRAE KSKTRRHLLE FWMVEPEVAP SNHKQNMDLQ 250 260 270 280 290 300 ERFVSFLVRR ALDECTVELE MLGRDLSKLK GAAEGNYPRV TYTEALEIVR QHIENKDLPP 310 320 330 340 350 360 NVQEDVQPVE WGDDLGAPHE TILGHHFDRP VMIEKYPAAI KAFYMQPDPE DSRVALCDDM 370 380 390 400 410 420 IAPEGYGEII GGSERIHDYD LLKSRIEHEG LPLEAFDWYL DLRRVGSVPH AGFGMGLERV 430 440 IAWISGIDHI REAIPFPRML TRMRP

References

[1]

"Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti." de Groot A., Dulermo R., Ortet P., Blanchard L., Guerin P., Fernandez B., Vacherie B., Dossat C., Jolivet E., Siguier P., Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W., Armengaud J. PLoS Genet. 5:E1000434-E1000434(2009) [PubMed: 19370165] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VCD115 / DSM 17065 / LMG 22923.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001114 Genomic DNA. Translation: ACO46043.1.
RefSeq	YP_002785797.1. NC_012526.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1CV26.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7738361.
GenomeReviews	Gene locus Deide_11380 in contig CP001114_GR.
KEGG	ddr:Deide_11380.
PATRIC	21616034. VBIDeiDes121019_1298.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DHLPQET.
ProtClustDB	PRK03932.
Family and domain databases
HAMAP	MF_00534. Asn_tRNA_synth. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR004522. Asn-tRNA-synth_IIb. IPR002312. Asp/Asn-tRNA-synth_IIb. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K01893.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF6. PTHR22594:SF6. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00457. AsnS. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYN_DEIDV

Accession

Primary (citable) accession number: C1CV26

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program