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C1CT52

- TRPF_STRZT

UniProt

C1CT52 - TRPF_STRZT

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Streptococcus pneumoniae (strain Taiwan19F-14)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSPNE487213:GI07-1693-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:SPT_1736
    OrganismiStreptococcus pneumoniae (strain Taiwan19F-14)
    Taxonomic identifieri487213 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000007961: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 199199N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197128Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi487213.SPT_1736.

    Structurei

    3D structure databases

    ProteinModelPortaliC1CT52.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiPDYAGFV.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C1CT52-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKVKICGLS TKEAVETAVS AGADYIGFVF APSKRQVTLE EAAELAKLIP    50
    ADVKKVGVFV SPSRVELLEA IDKVGLDLVQ VHGQVAADLF ENLPCASIQA 100
    VQVDGNGHVP NSQADYLLFD APVAGSGQSF DWGQLDTTGL AQPFFIAGGL 150
    NEDNVVKAIQ HFTPYAVDVS SGVETDGQKD HEKIRRFIER VKHGISGTK 199
    Length:199
    Mass (Da):21,236
    Last modified:May 26, 2009 - v1
    Checksum:iA0EB9CED2895ED9D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000921 Genomic DNA. Translation: ACO22268.1.
    RefSeqiYP_002743124.1. NC_012469.1.

    Genome annotation databases

    EnsemblBacteriaiACO22268; ACO22268; SPT_1736.
    GeneIDi7685355.
    KEGGisnt:SPT_1736.
    PATRICi19712699. VBIStrPne22502_1791.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000921 Genomic DNA. Translation: ACO22268.1 .
    RefSeqi YP_002743124.1. NC_012469.1.

    3D structure databases

    ProteinModelPortali C1CT52.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 487213.SPT_1736.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO22268 ; ACO22268 ; SPT_1736 .
    GeneIDi 7685355.
    KEGGi snt:SPT_1736.
    PATRICi 19712699. VBIStrPne22502_1791.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi PDYAGFV.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SPNE487213:GI07-1693-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Streptococcus pneumoniae strain Taiwan19F-14."
      Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
      Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Taiwan19F-14.

    Entry informationi

    Entry nameiTRPF_STRZT
    AccessioniPrimary (citable) accession number: C1CT52
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3