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C1CRH1

- C1CRH1_STRZT

UniProt

C1CRH1 - C1CRH1_STRZT

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, SPT_1111
Organism
Streptococcus pneumoniae (strain Taiwan19F-14)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381 By similarityUniRule annotation
Active sitei561 – 5611 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciSPNE487213:GI07-1081-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SPT_1111Imported
OrganismiStreptococcus pneumoniae (strain Taiwan19F-14)Imported
Taxonomic identifieri487213 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000007961: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi487213.SPT_1111.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiIDIVAQK.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1CRH1-1 [UniParc]FASTAAdd to Basket

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MSLQKLENYS NKSVVQEEVL ILTELLEDIT KNMLAPETFE KIIQLKELST    50
QEDYQGLNRL VTSLSNDEMV YISRYFSILP LLINISEDVD LAYEINHQNN 100
IDQDYLGKLS TTIKLVAEKE NAVEILEHLN VVPVLTAHPT QVQRKSMLDL 150
TNHIHSLLRK YRDVKLGLIN KDKWYNDLRR YIEIIMQTDM IREKKLKVTN 200
EITNAMEYYN SSFLKAVPHL TTEYKRLAQA HGLNLKQAKP ITMGMWIGGD 250
RDGNPFVTAK TLKQSALTQC EVIMNYYDKK IYQLYREFSL STSIVNVSKQ 300
VREMARQSKD NSIYREKELY RRALFDIQSK IQATKTYLIE DEEVGTRYET 350
ANDFYKDLIA IRDSLLENKG ESLISGDFVE LLQAVEIFGF YLASIDMRQD 400
SSVYEACVAE LLKSAGIHSR YSELSEEEKC DLLLKELEED PRILSATHAE 450
KSELLAKELA IFKTARVLKD KLGDDVIRQT IISHATSLSD MLELAILLKE 500
VGLVDTERAR VQIVPLFETI EDLDHSEETM RKYLSLSLAK KWIDSRNNYQ 550
EIMLGYSDSN KDGGYLSSCW TLYKAQQQLT AIGDEFGVKV TFFHGRGGTV 600
GRGGGPTYEA ITSQPLKSIK DRIRLTEQGE VIGNKYGNKD AAYYNLEMLV 650
SAAINRMITH KKSDTNTPNR YEAIMDQVVD RSYDVYRDLV FGNEHFYDYF 700
FESSPIKAIS SFNIGSRPAA RKTITEIGGL RAIPWVFSWS QSRVMFPGWY 750
GVGSSFKEFI NKNPENIAIL RDMYQNWPFF QSLLSNVDMV LSKSNMNIAF 800
EYAKLCEDEQ VKAIYETILN EWQVTKNVIL AIEGHDELLA DNPYLKASLD 850
YRMPYFNILN YIQLELIKRQ RRGELSSDQE RLIHITINGI ATGLRNSG 898
Length:898
Mass (Da):103,280
Last modified:May 26, 2009 - v1
Checksum:i2F1E9BE3F09DFF68
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000921 Genomic DNA. Translation: ACO23599.1.
RefSeqiYP_002742543.1. NC_012469.1.

Genome annotation databases

EnsemblBacteriaiACO23599; ACO23599; SPT_1111.
GeneIDi7685939.
KEGGisnt:SPT_1111.
PATRICi19711392. VBIStrPne22502_1144.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000921 Genomic DNA. Translation: ACO23599.1 .
RefSeqi YP_002742543.1. NC_012469.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 487213.SPT_1111.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO23599 ; ACO23599 ; SPT_1111 .
GeneIDi 7685939.
KEGGi snt:SPT_1111.
PATRICi 19711392. VBIStrPne22502_1144.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi IDIVAQK.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci SPNE487213:GI07-1081-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain Taiwan19F-14."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Taiwan19F-14.

Entry informationi

Entry nameiC1CRH1_STRZT
AccessioniPrimary (citable) accession number: C1CRH1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: June 11, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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