Segregation and condensation protein A - Streptococcus pneumoniae (strain P1031)

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C1CMI6 (SCPA_STRZP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 28. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Segregation and condensation protein A

Gene names

Name:	scpA
Ordered Locus Names:	SPP_1876

Organism

Streptococcus pneumoniae (strain P1031) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves By similarity. HAMAP-Rule MF_01805
Subunit structure	Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA By similarity.
Subcellular location	Cytoplasm By similarity. Note: Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells By similarity.
Sequence similarities	Belongs to the ScpA family.

Ontologies

Keywords
Biological process	Cell cycle Cell division Chromosome partition
Cellular component	Cytoplasm
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological_process	DNA replication Inferred from electronic annotation. Source: HAMAP cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cell division Inferred from electronic annotation. Source: UniProtKB-KW chromosome segregation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

242

Segregation and condensation protein A HAMAP-Rule MF_01805

PRO_1000187576

Secondary structure

1

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242

Helix Strand Turn

Sequences

Sequence

Length

Mass (Da)

Tools

C1CMI6 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: F200571AD5DA440E
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242

28,270

        10         20         30         40         50         60 
MDIKLKDFEG PLDLLLHLVS KYQMDIYDVP ITEVIEQYLA YVSTLQAMRL EVTGEYMVMA 

        70         80         90        100        110        120 
SQLMLIKSRK LLPKVAEVTD LGDDLEQDLL SQIEEYRKFK LLGEHLEAKH QERAQYYSKA 

       130        140        150        160        170        180 
PTELIYEDAE LVHDKTTIDL FLAFSNILAK KKEEFAQNHT TILRDEYKIE DMMIIVKESL 

       190        200        210        220        230        240 
IGRDQLRLQD LFKEAQNVQE VITLFLATLE LIKTQELILV QEESFGDIYL MEKKEESQVP 


QS

References

[1]	"Complete genome sequence of Streptococcus pneumoniae strain P1031." Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: P1031.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000920 Genomic DNA. Translation: ACO21653.1.

RefSeq

YP_002738974.1. NC_012467.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4I98	X-ray	2.80	A	1-160	[»]

ModBase

Protein-protein interaction databases

STRING

488223.SPP_1876.

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

EnsemblBacteria

ACO21653; ACO21653; SPP_1876.

GeneID

KEGG

PATRIC

32461126. VBIStrPne91701_1957.

Organism-specific databases

CMR

Phylogenomic databases

eggNOG

HOGENOM

KO

OMA

ProtClustDB

Family and domain databases

HAMAP

MF_01805. ScpA.

InterPro

IPR003768. ScpA.
[Graphical view]

Pfam

PF02616. ScpA_ScpB. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

SCPA_STRZP

Accession

Primary (citable) accession number: C1CMI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 26, 2009
Last modified:	May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents