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Protein

Segregation and condensation protein B

Gene

scpB

Organism
Streptococcus pneumoniae (strain P1031)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Chromosome partition

Enzyme and pathway databases

BioCyciSPNE488223:GHE7-1838-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Segregation and condensation protein BUniRule annotation
Gene namesi
Name:scpBUniRule annotation
Ordered Locus Names:SPP_1875
OrganismiStreptococcus pneumoniae (strain P1031)
Taxonomic identifieri488223 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

  • Cytoplasm UniRule annotation

  • Note: Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 189189Segregation and condensation protein BPRO_1000187546Add
BLAST

Interactioni

Subunit structurei

Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.UniRule annotation

Structurei

Secondary structure

1
189
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 1311Combined sources
Turni14 – 174Combined sources
Helixi21 – 288Combined sources
Helixi32 – 4817Combined sources
Beta strandi54 – 596Combined sources
Beta strandi62 – 676Combined sources
Helixi69 – 713Combined sources
Helixi72 – 787Combined sources
Helixi83 – 853Combined sources
Helixi89 – 10113Combined sources
Beta strandi103 – 1053Combined sources
Helixi106 – 1138Combined sources
Helixi118 – 1269Combined sources
Beta strandi129 – 1357Combined sources
Beta strandi143 – 1475Combined sources
Helixi149 – 1557Combined sources
Helixi160 – 1623Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4I98X-ray2.80B/C1-183[»]
ProteinModelPortaliC1CMI5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ScpB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1386.
HOGENOMiHOG000242838.
KOiK06024.
OMAiENSGYIR.
OrthoDBiEOG6CZQQQ.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_01804. ScpB.
InterProiIPR005234. ScpB_csome_segregation.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04079. DUF387. 1 hit.
[Graphical view]
PIRSFiPIRSF019345. ScpB. 1 hit.
TIGRFAMsiTIGR00281. TIGR00281. 1 hit.

Sequencei

Sequence statusi: Complete.

C1CMI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLAKIEAL LFVAGEDGIR VRQLAELLSL PPTGIQQSLG KLAQKYEKDP
60 70 80 90 100
DSSLALIETS GAYRLVTKPQ FAEILKEYSK APINQSLSRA ALETLSIIAY
110 120 130 140 150
KQPITRIEID AIRGVNSSGA LAKLQAFDLI KEDGKKEVLG RPNLYVTTDY
160 170 180
FLDYMGINHL EELPVIDELE IQAQESQLFG ERIEEDENQ
Length:189
Mass (Da):21,038
Last modified:May 26, 2009 - v1
Checksum:iB69B8B46CAED599A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000920 Genomic DNA. Translation: ACO20208.1.
RefSeqiWP_000105310.1. NC_012467.1.

Genome annotation databases

EnsemblBacteriaiACO20208; ACO20208; SPP_1875.
KEGGispp:SPP_1875.
PATRICi32461124. VBIStrPne91701_1956.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000920 Genomic DNA. Translation: ACO20208.1.
RefSeqiWP_000105310.1. NC_012467.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4I98X-ray2.80B/C1-183[»]
ProteinModelPortaliC1CMI5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO20208; ACO20208; SPP_1875.
KEGGispp:SPP_1875.
PATRICi32461124. VBIStrPne91701_1956.

Phylogenomic databases

eggNOGiCOG1386.
HOGENOMiHOG000242838.
KOiK06024.
OMAiENSGYIR.
OrthoDBiEOG6CZQQQ.

Enzyme and pathway databases

BioCyciSPNE488223:GHE7-1838-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
HAMAPiMF_01804. ScpB.
InterProiIPR005234. ScpB_csome_segregation.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF04079. DUF387. 1 hit.
[Graphical view]
PIRSFiPIRSF019345. ScpB. 1 hit.
TIGRFAMsiTIGR00281. TIGR00281. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain P1031."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P1031.

Entry informationi

Entry nameiSCPB_STRZP
AccessioniPrimary (citable) accession number: C1CMI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: July 22, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.