C1CM36 (C1CM36_STRZP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361

Gene names

Ordered Locus Names:

SPP_1716

Organism

Streptococcus pneumoniae (strain P1031) [Complete proteome] [HAMAP]

Taxonomic identifier

488223 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361
Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361
Sequence similarities	Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis PIRNR PIRNR001361
Molecular function	Transferase PIRNR PIRNR001361 EMBL ACO20385.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1CM36 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 573CC7A247AD71ED	FASTA	343	38,753
	10 20 30 40 50 60 MAFIEKGQEI DMEVIKAETQ LSAEALRLKE SRDRELADII SGEDDRILLV IGPCSSDNEE 70 80 90 100 110 120 AVLEYARRLS ALQKKVADKI FMVMRVYTAK PRTNGDGYKG LVHQPDTSKA PSLINGLQAV 130 140 150 160 170 180 RQLHYRVITE TGLTTADEML YPSNLILVDD LVSYHAVGAR SVEDQEHRFV ASGIDAPVGM 190 200 210 220 230 240 KNPTSGNLGV MFNAIYAAQN KQTFLYHGQE VETSGNPLAH VILRGAVNEY GNYMPNYYYE 250 260 270 280 290 300 NLLQAIERYE TMGLENPFIL IDTNHDNSGK QYMEQIRIVR QTLQNRDWNE KIKKTVRGFM 310 320 330 340 IESYLADGRQ NQPEIFGCSI TDPCLGWENT EALVEEIYVT LTK

References

[1]	"Complete genome sequence of Streptococcus pneumoniae strain P1031." Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H. Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000920 Genomic DNA. Translation: ACO20385.1.
RefSeq	YP_002738824.1. NC_012467.1.
3D structure databases
ProteinModelPortal	C1CM36.
ModBase	Search...
Protein-protein interaction databases
STRING	C1CM36.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000081810; EBSTRP00000076344; EBSTRG00000080133.
GeneID	7682529.
GenomeReviews	Gene locus SPP_1716 in contig CP000920_GR.
KEGG	spp:SPP_1716.
PATRIC	32460773. VBIStrPne91701_1782.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000028141.
OMA	MDNSFKL.
ProtClustDB	PRK09261.
Enzyme and pathway databases
BioCyc	SPNE1313-1:SPP_1716-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006219. DHAP_synth_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01626.
PANTHER	PTHR21225. AroFGH. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
PIRSF	PIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMs	TIGR00034. AroFGH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1CM36_STRZP

Accession

Primary (citable) accession number: C1CM36

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)