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C1CE02

- PEPT_STRZJ

UniProt

C1CE02 - PEPT_STRZJ

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Protein
Peptidase T
Gene
pepT, SPJ_0948
Organism
Streptococcus pneumoniae (strain JJA)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cleaves the N-terminal amino acid of tripeptides By similarity.UniRule annotation

Catalytic activityi

Release of the N-terminal residue from a tripeptide.UniRule annotation

Cofactori

Binds 2 zinc ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi81 – 811Zinc 1 By similarity
Active sitei83 – 831 By similarity
Metal bindingi142 – 1421Zinc 1 By similarity
Metal bindingi142 – 1421Zinc 2 By similarity
Active sitei176 – 1761Proton acceptor By similarity
Metal bindingi177 – 1771Zinc 2 By similarity
Metal bindingi199 – 1991Zinc 1 By similarity
Metal bindingi381 – 3811Zinc 2 By similarity

GO - Molecular functioni

  1. metallopeptidase activity Source: UniProtKB-KW
  2. tripeptide aminopeptidase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. peptide metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminopeptidase, Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciSPNE488222:GI12-930-MONOMER.

Protein family/group databases

MEROPSiM20.003.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidase T (EC:3.4.11.4)
Alternative name(s):
Aminotripeptidase
Short name:
Tripeptidase
Tripeptide aminopeptidase
Gene namesi
Name:pepT
Ordered Locus Names:SPJ_0948
OrganismiStreptococcus pneumoniae (strain JJA)
Taxonomic identifieri488222 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002206: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Peptidase TUniRule annotation
PRO_1000200901Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi488222.SPJ_0948.

Structurei

3D structure databases

ProteinModelPortaliC1CE02.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M20B family.

Phylogenomic databases

eggNOGiCOG2195.
HOGENOMiHOG000032390.
KOiK01258.
OMAiHENYDGE.
OrthoDBiEOG6SV59Q.

Family and domain databases

Gene3Di3.30.70.360. 1 hit.
HAMAPiMF_00550. Aminopeptidase_M20.
InterProiIPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
IPR010161. Peptidase_M20B.
[Graphical view]
PfamiPF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view]
PIRSFiPIRSF037215. Peptidase_M20B. 1 hit.
SUPFAMiSSF55031. SSF55031. 1 hit.
TIGRFAMsiTIGR01882. peptidase-T. 1 hit.
PROSITEiPS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1CE02-1 [UniParc]FASTAAdd to Basket

« Hide

MTYPNLLDRF LTYVKVNTRS DEHSTTTPST QSQVDFATNV LIPEMKRVGL    50
QNVYYLPNGF AIGTLPANDP SLTRKIGFIS HMDTADFNAE GVNPQVIENY 100
DGGVIELGNS GFKLDPADFK SLEKYPGQTL ITTDGTSLLG ADDKSGIAEI 150
MTTIEYLTAH PEIKHCEIRV GFGPDEEIGV GANKFDAEDF DVDFAYTVDG 200
GPLGELQYET FSAAGAELHF QGRNVHPGTA KGQMVNALQL AIDFHNQLPE 250
NDRPELTEGY QGFYHLMDVT GSVEEVRASY IIRDFEKDAF EARKASMQSI 300
ADKMNEELGS DRVTLNLTDQ YYNMKEVIEK DMTPITIAKA VMEDLGITPI 350
IEPIRGGTDG SKISFMGIPT PNIFAGGENM HGRFEYVSLQ TMERAVDTII 400
GIVAYKG 407
Length:407
Mass (Da):44,833
Last modified:May 26, 2009 - v1
Checksum:i8A3C0DD750881344
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000919 Genomic DNA. Translation: ACO20120.1.
RefSeqiYP_002736023.1. NC_012466.1.

Genome annotation databases

EnsemblBacteriaiACO20120; ACO20120; SPJ_0948.
GeneIDi7678667.
KEGGisjj:SPJ_0948.
PATRICi19697044. VBIStrPne71544_1004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000919 Genomic DNA. Translation: ACO20120.1 .
RefSeqi YP_002736023.1. NC_012466.1.

3D structure databases

ProteinModelPortali C1CE02.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 488222.SPJ_0948.

Protein family/group databases

MEROPSi M20.003.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO20120 ; ACO20120 ; SPJ_0948 .
GeneIDi 7678667.
KEGGi sjj:SPJ_0948.
PATRICi 19697044. VBIStrPne71544_1004.

Phylogenomic databases

eggNOGi COG2195.
HOGENOMi HOG000032390.
KOi K01258.
OMAi HENYDGE.
OrthoDBi EOG6SV59Q.

Enzyme and pathway databases

BioCyci SPNE488222:GI12-930-MONOMER.

Family and domain databases

Gene3Di 3.30.70.360. 1 hit.
HAMAPi MF_00550. Aminopeptidase_M20.
InterProi IPR001261. ArgE/DapE_CS.
IPR002933. Peptidase_M20.
IPR011650. Peptidase_M20_dimer.
IPR010161. Peptidase_M20B.
[Graphical view ]
Pfami PF07687. M20_dimer. 1 hit.
PF01546. Peptidase_M20. 1 hit.
[Graphical view ]
PIRSFi PIRSF037215. Peptidase_M20B. 1 hit.
SUPFAMi SSF55031. SSF55031. 1 hit.
TIGRFAMsi TIGR01882. peptidase-T. 1 hit.
PROSITEi PS00758. ARGE_DAPE_CPG2_1. 1 hit.
PS00759. ARGE_DAPE_CPG2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain JJA."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JJA.

Entry informationi

Entry nameiPEPT_STRZJ
AccessioniPrimary (citable) accession number: C1CE02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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