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C1C967

- TRPF_STRP7

UniProt

C1C967 - TRPF_STRP7

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, SP70585_1874
Organism
Streptococcus pneumoniae (strain 70585)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciSPNE488221:GH4U-1832-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:SP70585_1874
OrganismiStreptococcus pneumoniae (strain 70585)
Taxonomic identifieri488221 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002211: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_1000197124Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi488221.SP70585_1874.

Structurei

3D structure databases

ProteinModelPortaliC1C967.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

C1C967-1 [UniParc]FASTAAdd to Basket

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MTKVKICGLS TKEAVETAVS AGADYIGFVF APSKRQVTLE EAAELAKLIP    50
ADVKKVGVFV SPSRVELLEA IDKVGLDLVQ VHGQVADDLF ENLPCASIQA 100
VQVDGNGHVP NSQADYLLFD APVAGSGQPF DWGQLDTTGL AQPFFIAGGL 150
NEDNVVKAIQ HFTPYAVDVS SGVETDGQKD HEKIRRFIER VKHGISGTK 199
Length:199
Mass (Da):21,290
Last modified:May 26, 2009 - v1
Checksum:iFC333B4F9E4E8422
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000918 Genomic DNA. Translation: ACO16311.1.
RefSeqiYP_002741093.1. NC_012468.1.

Genome annotation databases

EnsemblBacteriaiACO16311; ACO16311; SP70585_1874.
GeneIDi7683226.
KEGGisnm:SP70585_1874.
PATRICi19670156. VBIStrPne83895_1940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000918 Genomic DNA. Translation: ACO16311.1 .
RefSeqi YP_002741093.1. NC_012468.1.

3D structure databases

ProteinModelPortali C1C967.
ModBasei Search...

Protein-protein interaction databases

STRINGi 488221.SP70585_1874.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACO16311 ; ACO16311 ; SP70585_1874 .
GeneIDi 7683226.
KEGGi snm:SP70585_1874.
PATRICi 19670156. VBIStrPne83895_1940.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci SPNE488221:GH4U-1832-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain 70585."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 70585.

Entry informationi

Entry nameiTRPF_STRP7
AccessioniPrimary (citable) accession number: C1C967
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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