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Protein
Submitted name:

Neuraminidase

Gene

SP70585_1731

Organism
Streptococcus pneumoniae (strain 70585)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-sialidase activity Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciSPNE488221:GH4U-1691-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
NeuraminidaseImported
Gene namesi
Ordered Locus Names:SP70585_1731Imported
OrganismiStreptococcus pneumoniae (strain 70585)Imported
Taxonomic identifieri488221 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002211: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi488221.SP70585_1731.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000284737.
KOiK01186.
OMAiGGPKREN.
OrthoDBiEOG61CM2G.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1C8T0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIVGAVVFGT SPVLAQEGAS EQPLANETQL SGESSTLTDT EKSQPSSETE
60 70 80 90 100
LSGNKQEQER KDKQEEKIPR DYYARDLENV ETVIEKEDVE TNASNGQRVD
110 120 130 140 150
LSSELDKLKK LENATVHMEF KPDASAPRFY NLFSVSSDTK ENEYFTMSVL
160 170 180 190 200
DNTALIEGRG ANGEQFYDKY TDAPLKVRPG QWNSVTFTVE QPTAELPHGR
210 220 230 240 250
VRLYVNGVLS RTSLKSGNFI KDMPDVNQAQ LGATKRGNKT VWGSNLQVRN
260 270 280 290 300
LTVYDRALSP EEVQTRSQLF ERGDLEKKLP EGAKISEKED VFEGGMNNKP
310 320 330 340 350
NKDGIKSYRI PALLKTDKGT LIAGADERRL HSSDWGDIGM VIRRSEDNGK
360 370 380 390 400
TWGDRVTITN LRDNPKASDP SIGSPVNIDM VLVQDPETKR IFSIYDMFPE
410 420 430 440 450
GKGIFGMSSQ KEEAYKKIDG KTYQILYREG EKGAYTIREN GTVYTPDGKA
460 470 480 490 500
TDYRVVVDPV KPAYSDKGDL YKGDQLLGNI YFTTNKTSPF RIAKDSYLWM
510 520 530 540 550
SYSDDDGKTW SAPQDITPMV KADWMKFLGV GPGTGIVLRN GPHKGRILIP
560 570 580 590 600
VYTTNNVSHL NGSQSSRVIY SDDHGKTWHA GEAVNDNRQV DGQKIHSSTM
610 620 630 640 650
NNRRAQNTES TVVQLNNGDV KLFMRGLTGD LQVATSKDGG VTWEKDIKRY
660 670 680 690 700
PQVKDVYVQM SAIHTMHNGK EYIILSNAGG PKRENGMVHL ARVEENGELT
710 720 730 740 750
WLKHNPIQKG EFAYNSLQEL GNGEYGILYE HTEKGQNAYT LSFRKFNWEF
760 770 780 790 800
LSKNLISPTE AKVKRTREMG KGEMGKGVIG LEFDSEVLVN KAPTLQLANG
810 820 830 840 850
KTATFLTQYD SKTLLFAVDK EDIGQEIIGI AKGSIESMHN LPVNLAGARV
860 870 880 890 900
PGGVNGSKAA VHEVPEFTGG VNGTEPAVHE IAEYKGSDSL VTLTTKEDYT
910 920 930 940
YKAPLAQQAL PETGNKESDL LASLGLTAFF LGLFTLGKKE RTIREEF
Length:947
Mass (Da):105,154
Last modified:May 26, 2009 - v1
Checksum:i3E0AB60C73102BE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000918 Genomic DNA. Translation: ACO17645.1.
RefSeqiYP_002740956.1. NC_012468.1.

Genome annotation databases

EnsemblBacteriaiACO17645; ACO17645; SP70585_1731.
GeneIDi7683195.
KEGGisnm:SP70585_1731.
PATRICi19669849. VBIStrPne83895_1787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000918 Genomic DNA. Translation: ACO17645.1.
RefSeqiYP_002740956.1. NC_012468.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi488221.SP70585_1731.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO17645; ACO17645; SP70585_1731.
GeneIDi7683195.
KEGGisnm:SP70585_1731.
PATRICi19669849. VBIStrPne83895_1787.

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000284737.
KOiK01186.
OMAiGGPKREN.
OrthoDBiEOG61CM2G.

Enzyme and pathway databases

BioCyciSPNE488221:GH4U-1691-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR004124. Glyco_hydro_33_N.
IPR001791. Laminin_G.
IPR019931. LPXTG_anchor.
IPR026856. Sialidase_fam.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PfamiPF02973. Sialidase. 1 hit.
[Graphical view]
SMARTiSM00282. LamG. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain 70585."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 70585Imported.

Entry informationi

Entry nameiC1C8T0_STRP7
AccessioniPrimary (citable) accession number: C1C8T0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: January 7, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.