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C1C7B7

- GLGA_STRP7

UniProt

C1C7B7 - GLGA_STRP7

Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus pneumoniae (strain 70585)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (26 May 2009)
      Previous versions | rss
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    Functioni

    Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

    Catalytic activityi

    ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei15 – 151ADP-glucoseUniRule annotation

    GO - Molecular functioni

    1. starch synthase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Glycogen biosynthesis

    Enzyme and pathway databases

    BioCyciSPNE488221:GH4U-1166-MONOMER.
    UniPathwayiUPA00164.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
    Alternative name(s):
    Starch [bacterial glycogen] synthaseUniRule annotation
    Gene namesi
    Name:glgAUniRule annotation
    Ordered Locus Names:SP70585_1194
    OrganismiStreptococcus pneumoniae (strain 70585)
    Taxonomic identifieri488221 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000002211: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 477477Glycogen synthasePRO_1000190084Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi488221.SP70585_1194.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0297.
    HOGENOMiHOG000294940.
    KOiK00703.
    OMAiPYHDESQ.
    OrthoDBiEOG6JTC6Z.

    Family and domain databases

    HAMAPiMF_00484. Glycogen_synth.
    InterProiIPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view]
    PfamiPF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02095. glgA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C1C7B7-1 [UniParc]FASTAAdd to Basket

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    MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK    50
    FGSQIEDVLH FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG 100
    DFDDGERFAF FQLAAIEAME RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI 150
    QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF GVGFERYADG TLRWNNCLNW 200
    MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDQILKMESG KVSGIVNGID 250
    ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR ADVPLVGIVS 300
    RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL 350
    STNITFDVKL AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG 400
    GLRDTVRAFN PIEGSGTGFS FDNLSPYWLN WTFQTALDLY RNHPDIWRNL 450
    QKQAMESDFS WDTACKSYLD LYHSLVN 477
    Length:477
    Mass (Da):54,132
    Last modified:May 26, 2009 - v1
    Checksum:iBACE24A12669B870
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000918 Genomic DNA. Translation: ACO17357.1.
    RefSeqiYP_002740443.1. NC_012468.1.

    Genome annotation databases

    EnsemblBacteriaiACO17357; ACO17357; SP70585_1194.
    GeneIDi7682990.
    KEGGisnm:SP70585_1194.
    PATRICi19668741. VBIStrPne83895_1234.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000918 Genomic DNA. Translation: ACO17357.1 .
    RefSeqi YP_002740443.1. NC_012468.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 488221.SP70585_1194.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACO17357 ; ACO17357 ; SP70585_1194 .
    GeneIDi 7682990.
    KEGGi snm:SP70585_1194.
    PATRICi 19668741. VBIStrPne83895_1234.

    Phylogenomic databases

    eggNOGi COG0297.
    HOGENOMi HOG000294940.
    KOi K00703.
    OMAi PYHDESQ.
    OrthoDBi EOG6JTC6Z.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .
    BioCyci SPNE488221:GH4U-1166-MONOMER.

    Family and domain databases

    HAMAPi MF_00484. Glycogen_synth.
    InterProi IPR001296. Glyco_trans_1.
    IPR011835. Glycogen/starch_synth.
    IPR013534. Starch_synth_cat_dom.
    [Graphical view ]
    Pfami PF08323. Glyco_transf_5. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02095. glgA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Streptococcus pneumoniae strain 70585."
      Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
      Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 70585.

    Entry informationi

    Entry nameiGLGA_STRP7
    AccessioniPrimary (citable) accession number: C1C7B7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: May 26, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3