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Protein

Glycogen synthase

Gene

glgA

Organism
Streptococcus pneumoniae (strain 70585)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciSPNE488221:GH4U-1166-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:SP70585_1194
OrganismiStreptococcus pneumoniae (strain 70585)
Taxonomic identifieri488221 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002211 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 477477Glycogen synthasePRO_1000190084Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

C1C7B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK
60 70 80 90 100
FGSQIEDVLH FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG
110 120 130 140 150
DFDDGERFAF FQLAAIEAME RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI
160 170 180 190 200
QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF GVGFERYADG TLRWNNCLNW
210 220 230 240 250
MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDQILKMESG KVSGIVNGID
260 270 280 290 300
ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR ADVPLVGIVS
310 320 330 340 350
RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL
360 370 380 390 400
STNITFDVKL AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG
410 420 430 440 450
GLRDTVRAFN PIEGSGTGFS FDNLSPYWLN WTFQTALDLY RNHPDIWRNL
460 470
QKQAMESDFS WDTACKSYLD LYHSLVN
Length:477
Mass (Da):54,132
Last modified:May 26, 2009 - v1
Checksum:iBACE24A12669B870
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000918 Genomic DNA. Translation: ACO17357.1.
RefSeqiWP_000697313.1. NC_012468.1.
YP_002740443.1. NC_012468.1.

Genome annotation databases

EnsemblBacteriaiACO17357; ACO17357; SP70585_1194.
KEGGisnm:SP70585_1194.
PATRICi19668741. VBIStrPne83895_1234.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000918 Genomic DNA. Translation: ACO17357.1.
RefSeqiWP_000697313.1. NC_012468.1.
YP_002740443.1. NC_012468.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACO17357; ACO17357; SP70585_1194.
KEGGisnm:SP70585_1194.
PATRICi19668741. VBIStrPne83895_1234.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciSPNE488221:GH4U-1166-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Streptococcus pneumoniae strain 70585."
    Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
    Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 70585.

Entry informationi

Entry nameiGLGA_STRP7
AccessioniPrimary (citable) accession number: C1C7B7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: June 24, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.