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C1C6I9 (C1C6I9_STRP7) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Branched-chain-amino-acid aminotransferase RuleBase RU004517
EC=2.6.1.42 RuleBase RU004517
Gene names
Name:ilvE EMBL ACO16317.1
Ordered Locus Names:SP70585_0891
OrganismStreptococcus pneumoniae (strain 70585) [Complete proteome] [HAMAP] EMBL ACO16317.1
Taxonomic identifier488221 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length340 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate. RuleBase RU004517

L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate. RuleBase RU004517

L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate. RuleBase RU004517

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU004516

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.

Sequence similarities

Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU004106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue1841N6-(pyridoxal phosphate)lysine By similarity PIRSR PIRSR006468-1

Sequences

Sequence LengthMass (Da)Tools
C1C6I9 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: AB498C9E0052B0EE

FASTA34037,473
        10         20         30         40         50         60 
MTVTIDWENL GFSYMKLPYR YLAHFKNGQW DQGELTEDAT LHISESSPSL HYGQQAFEGL 

        70         80         90        100        110        120 
KAYRTKDGSV QLFRPDENAK RLQRTCDRLL MPQVPTDMFV EACKAVVRAN EEYVPPYGTG 

       130        140        150        160        170        180 
GTLYLRPLLI GVGDIIGVKP AEEYIFTIFA MPVGNYFKGG LVPTNFLIQD EYDRAAPNGT 

       190        200        210        220        230        240 
GAAKVGGNYA ASLLPGKMAK SRHFSDVIYL DPSTHTKIEE VGSANFFGIT ADNEFVTPLS 

       250        260        270        280        290        300 
PSILPSITKY SLLYLAEHRL GLTPIEGDVP IDNLDRFVEA GACGTAAVIS PIGGIQHGDD 

       310        320        330        340 
FHVFYSETEV GPVTRKLYNE LTGIQFGDIE APEGWIVKVD

« Hide

References

[1]"Complete genome sequence of Streptococcus pneumoniae strain 70585."
Hotopp J.D., Censini S., Masignani V., Covacci A., Tettelin H.
Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 70585.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000918 Genomic DNA. Translation: ACO16317.1.
RefSeqYP_002740165.1. NC_012468.1.

3D structure databases

ProteinModelPortalC1C6I9.
ModBaseSearch...

Protein-protein interaction databases

STRING488221.SP70585_0891.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACO16317; ACO16317; SP70585_0891.
GeneID7684690.
KEGGsnm:SP70585_0891.
PATRIC19668114. VBIStrPne83895_0925.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0115.
HOGENOMHOG000276704.
KOK00826.
OMAMNVFFVM.
ProtClustDBPRK13357.

Enzyme and pathway databases

UniPathwayUPA00047; UER00058.
UPA00048; UER00073.
UPA00049; UER00062.

Family and domain databases

InterProIPR001544. Aminotrans_IV.
IPR018300. Aminotrans_IV_CS.
IPR005786. B_amino_transII.
[Graphical view]
PANTHERPTHR11825. PTHR11825. 1 hit.
PTHR11825:SF2. PTHR11825:SF2. 1 hit.
PfamPF01063. Aminotran_4. 1 hit.
[Graphical view]
PIRSFPIRSF006468. BCAT1. 1 hit.
SUPFAMSSF56752. Aminotrans_IV. 1 hit.
TIGRFAMsTIGR01123. ilvE_II. 1 hit.
PROSITEPS00770. AA_TRANSFER_CLASS_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1C6I9_STRP7
AccessionPrimary (citable) accession number: C1C6I9
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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