Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C1BE29

- ACDH6_RHOOB

UniProt

C1BE29 - ACDH6_RHOOB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Acetaldehyde dehydrogenase 6

Gene

ROP_pROB02-02250

Organism
Rhodococcus opacus (strain B4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD+ and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.UniRule annotation

Catalytic activityi

Acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei133 – 1331Acyl-thioester intermediateUniRule annotation
Binding sitei297 – 2971NADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 184NADUniRule annotation
Nucleotide bindingi164 – 1729NADUniRule annotation

GO - Molecular functioni

  1. acetaldehyde dehydrogenase (acetylating) activity Source: UniProtKB-HAMAP
  2. NAD binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic compound catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciROPA632772:GH0Q-8126-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetaldehyde dehydrogenase 6UniRule annotation (EC:1.2.1.10UniRule annotation)
Alternative name(s):
Acetaldehyde dehydrogenase [acetylating] 6UniRule annotation
Gene namesi
Ordered Locus Names:ROP_pROB02-02250
Encoded oniPlasmid pROB020 Publication
OrganismiRhodococcus opacus (strain B4)
Taxonomic identifieri632772 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002212: Plasmid pROB02

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 327327Acetaldehyde dehydrogenase 6PRO_0000387725Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC1BE29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the acetaldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000052149.
KOiK04073.
OMAiFTETTAH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01657. Ac_ald_DH_ac.
InterProiIPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view]
PfamiPF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view]
PIRSFiPIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTiSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03215. ac_ald_DH_ac. 1 hit.

Sequencei

Sequence statusi: Complete.

C1BE29-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSENTRKVTV AVIGSGNIGT DLMIKVIRHS DVLQMGAMVG IDPDSDGLAR
60 70 80 90 100
ARRLGVPTTA VGVHGLLELP NFDEIDVVFD ATSAKAHAAN AALLEPLGKR
110 120 130 140 150
LIDLTPAALG PFVVPAVNLD EHRHAANVNM VTCGGQATIP IVAAVSRVTP
160 170 180 190 200
VAYAEIVASI ASKSAGPGTR ANIDEFTETT SHAIETVGGA RRGKAIIVLN
210 220 230 240 250
PADPPLIMRD TVLCLISARD PATHDAIRNS IQAMVEHVAT YVPGYRLKQQ
260 270 280 290 300
VQITPVPDGQ PVHTLLASGD TAAPTHQVSV FLEVEGAAHY LPAYAGNLDI
310 320
MTSAAVRYAE SVADTIAAPA ATQGATR
Length:327
Mass (Da):34,054
Last modified:May 26, 2009 - v1
Checksum:iF0DAF5DDEA10DE2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011117 Genomic DNA. Translation: BAH47232.1.
RefSeqiWP_012687258.1. NC_012521.1.
YP_002777169.1. NC_012521.1.

Genome annotation databases

EnsemblBacteriaiBAH47232; BAH47232; ROP_pROB02-02250.
GeneIDi7737218.
KEGGirop:ROP_pROB02-02250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011117 Genomic DNA. Translation: BAH47232.1 .
RefSeqi WP_012687258.1. NC_012521.1.
YP_002777169.1. NC_012521.1.

3D structure databases

ProteinModelPortali C1BE29.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAH47232 ; BAH47232 ; ROP_pROB02-02250 .
GeneIDi 7737218.
KEGGi rop:ROP_pROB02-02250.

Phylogenomic databases

HOGENOMi HOG000052149.
KOi K04073.
OMAi FTETTAH.

Enzyme and pathway databases

BioCyci ROPA632772:GH0Q-8126-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_01657. Ac_ald_DH_ac.
InterProi IPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view ]
Pfami PF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view ]
PIRSFi PIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTi SM00859. Semialdhyde_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03215. ac_ald_DH_ac. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B4.

Entry informationi

Entry nameiACDH6_RHOOB
AccessioniPrimary (citable) accession number: C1BE29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 26, 2009
Last modified: October 1, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3