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C1BA80 (C1BA80_RHOOB) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00252 RuleBase RU000336
EC=6.1.1.6 HAMAP-Rule MF_00252 RuleBase RU000336
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00252
Gene names
Name:lysS HAMAP-Rule MF_00252 EMBL BAH52583.1
Ordered Locus Names:ROP_43360 EMBL BAH52583.1
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP] EMBL BAH52583.1
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus ›

Protein attributes

Sequence length503 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00252 SAAS SAAS002313

Cofactor

Binds 3 magnesium ions per subunit By similarity. HAMAP-Rule MF_00252

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00252 SAAS SAAS002313

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00252.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00252 RuleBase RU003746

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding4131Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4201Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4201Magnesium 2 By similarity HAMAP-Rule MF_00252

Sequences

Sequence LengthMass (Da)Tools
C1BA80 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 969BD270714761F0

FASTA50355,904
        10         20         30         40         50         60 
MSEVAAQPVD DTPEQLRIRQ EKRERILAEG REAYPVSVAR THSLAEIRAK YPELEPDTAT 

        70         80         90        100        110        120 
GDQVGIVGRV IFVRNTGKLC FATLQEGDGT QLQAMISLAA VGEDALASWK ADVDLGDFVF 

       130        140        150        160        170        180 
VHGEVISSRR GELSVMADSW QIASKSLRPL PVAHKEMNEE SRVRQRYADL IVRPEARDNA 

       190        200        210        220        230        240 
RKRVSVVREL RNALERRGFL EVETPMLQTV AGGAAARPFI THSNALDIDL YLRIAPELFL 

       250        260        270        280        290        300 
KRCVVGGIEK VFEINRNFRN EGVDSTHSPE FAMLETYEAY GTYDDSAVMI RELVQEVAQA 

       310        320        330        340        350        360 
AFGSQVVTLA DGTEYDLSGE WKTLEMYPSL SQAIGVDVTP DTTVEELLAL AEKVGLEVPK 

       370        380        390        400        410        420 
DKGYGHGKLV EELWEHQCGD QLFEPTFVRD FPVETSPLTR DHRSKAGVTE KWDLYIRGFE 

       430        440        450        460        470        480 
LATGYSELVD PVIQRERFVD QARLASAGDD EAMALDEEFL AAMEQGMPPT TGTGMGIDRL 

       490        500 
LMALTGLGIR ETILFPIVRP SSR

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B4 EMBL BAH52583.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011115 Genomic DNA. Translation: BAH52583.1.
RefSeqYP_002781528.1. NC_012522.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING632772.ROP_43360.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAH52583; BAH52583; ROP_43360.
GeneID7743056.
KEGGrop:ROP_43360.
PATRIC23225991. VBIRhoOpa21106_4373.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1190.
HOGENOMHOG000236578.
KOK04567.
OMAEHKLEQP.
ProtClustDBPRK00484.

Enzyme and pathway databases

BioCycROPA632772:GH0Q-6738-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00252. Lys_tRNA_synth_class2.
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR002313. Lys-tRNA-ligase_II.
IPR018149. Lys-tRNA-synth_II_C.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
PANTHERPTHR22594. PTHR22594. 1 hit.
PTHR22594:SF4. PTHR22594:SF4. 1 hit.
PfamPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR00982. TRNASYNTHLYS.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMsTIGR00499. lysS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1BA80_RHOOB
AccessionPrimary (citable) accession number: C1BA80
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info