C1B8Y6 (C1B8Y6_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401 EMBL BAH52139.1
Ordered Locus Names:	ROP_38920

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 SAAS SAAS002569 EMBL BAH52139.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	46	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	C1B8Y6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 4AAD528C4D3229C8	FASTA	221	24,208
	10 20 30 40 50 60 MMVTAEDALP GRSQPIPVPA THFVNGHPLK PPFPEGLQTA VLGMGCFWGA EKEFWQLDGV 70 80 90 100 110 120 YTTAVGYAGG YTPNPTYEET CSGRTGHTEV VLVVFDPKVI SYAEILKEFW ENHDPTQGMR 130 140 150 160 170 180 QGNDQGTQYR SAIYTIDEQQ VEIAEATGEA FEKRLAEAGY GAITTEIAPL TQFYYAEDYH 190 200 210 220 QQYLAKNPGG YCPVHATGVS CPVGLLKQDE VPAQTDILPP S

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH52139.1.
RefSeq	YP_002781084.1. NC_012522.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1B8Y6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7747497.
GenomeReviews	Gene locus ROP_38920 in contig AP011115_GR.
KEGG	rop:ROP_38920.
PATRIC	23225077. VBIRhoOpa21106_3925.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	QETSFEQ.
ProtClustDB	CLSK2469141.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1B8Y6_RHOOB

Accession

Primary (citable) accession number: C1B8Y6

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)