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C1B4I8 (C1B4I8_RHOOB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Name:pyrC EMBL BAH55177.1
Ordered Locus Names:ROP_69300
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP]
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length442 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
C1B4I8 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 223FF5BBA3343160

FASTA44246,559
        10         20         30         40         50         60 
MTGETVLIKN VLLYGEGEPT DVLLGDGVIA AIGADAGKEA APDAEVIDAA GQILLPGFVD 

        70         80         90        100        110        120 
LHTHLREPGR EDTETIDSGS AAAALGGYTA VFAMANTSPV ADSVVVTDHV WRRGQEVGLV 

       130        140        150        160        170        180 
DVHPVGAVTV GLEGKQLAEM ATMASGTGRV RMFSDDGHCV YDPLIMRRAL EYSSSLGVLI 

       190        200        210        220        230        240 
AQHAEEPRLT VGAIAHEGPT AARLGLAGWP RAAEESIVAR DALLARDAGA RVHICHASTA 

       250        260        270        280        290        300 
GTVELMKWAR GQGISITAEV TPHHLLLDDS RLETYDAVNK VNPPLREASD VAALRAGLAE 

       310        320        330        340        350        360 
GTIDCVATDH APHAEQDKCC EFAAARPGML GLETALSIVV QTMVRTGLLD WRGVARVMSE 

       370        380        390        400        410        420 
RPAEIVGLDD QGRPIEVGEP ANLVLIDPDA EWTVHGPDLA SVAHNTPYES MTLPARVTTT 

       430        440 
ILRGRITASD GQARVRVRNG RG

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011115 Genomic DNA. Translation: BAH55177.1.
RefSeqYP_002784122.1. NC_012522.1.

3D structure databases

ProteinModelPortalC1B4I8.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1B4I8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7744493.
GenomeReviewsGene locus ROP_69300 in contig AP011115_GR.
KEGGrop:ROP_69300.
PATRIC23231313. VBIRhoOpa21106_7015.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMANTPYESM.
ProtClustDBPRK09357.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1B4I8_RHOOB
AccessionPrimary (citable) accession number: C1B4I8
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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