C1B454 (C1B454_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase 2 HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein 2 HAMAP MF_00259

Gene names

Name:	gcvT EMBL BAH50902.1
Synonyms:	gcvT2 HAMAP MF_00259
Ordered Locus Names:	ROP_26550

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 SAAS SAAS022903 RuleBase RU003981 Methyltransferase EMBL BAH50902.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1B454 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 9AAE060FE672DC8B	FASTA	371	39,259
	10 20 30 40 50 60 MTVTTTPASP LLGEHTALGA HFTDFAGWQM PLKYDSELAE HHAVRKTAGL FDLSHMGEIA 70 80 90 100 110 120 VTGTESGALL DYALAGELSK IGVGRAKYSL LCNADGGVID DLVVYRLANE HFLVVANASN 130 140 150 160 170 180 APAVYRELAA RAEGFSATVD DQSAETALIA VQGPAAQDIV RSLVPAPQVE TVAELKYYAV 190 200 210 220 230 240 TRAAVAGIDV LLARTGYTGE DGFELYVPNA QAVQLWRALL DATTAHDGVP AGLACRDTLR 250 260 270 280 290 300 LEAGMALYGH ELTLDTDPYE AGLGKVVRLN KEFVGRDALQ ALSEQAPQRV LVGLAGTGRR 310 320 330 340 350 360 AARADYTVHD TTSGTAVGTI TSGALSPTLG HPIALAFVDI AFREPGTELT VDIRGKKEPF 370 VVTPSPFYRR S

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH50902.1.
RefSeq	YP_002779847.1. NC_012522.1.
3D structure databases
ProteinModelPortal	C1B454.
ModBase	Search...
Protein-protein interaction databases
STRING	C1B454.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7744370.
GenomeReviews	Gene locus ROP_26550 in contig AP011115_GR.
KEGG	rop:ROP_26550.
PATRIC	23222585. VBIRhoOpa21106_2685.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	KALYGGM.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1B454_RHOOB

Accession

Primary (citable) accession number: C1B454

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)