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C1B1F1 (AROA_RHOOB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:ROP_63990
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP]
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4384383-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000124703

Sequences

Sequence LengthMass (Da)Tools
C1B1F1 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: B376EDBFD8250094

FASTA43845,033
        10         20         30         40         50         60 
METVSLSLWN APRAEAPVVA TVALPGSKSI TNRALILAAL ADGPSTLTGA LRSRDTDLMI 

        70         80         90        100        110        120 
DALRTLGIGI ETAGGDTTLR VAPGPLRGGA VDCGLAGTVM RFLPPVAALA GGTVDFDGDE 

       130        140        150        160        170        180 
QARTRPLDTI LNALRGLGAD IDGDSLPFTV RGAGSLRGGR VTIDASGSSQ FVSGLLLSAA 

       190        200        210        220        230        240 
AFDEGVTVHH DGTTVPSMPH IDMTVEMLRE SGVEVSTPAT GGEADTWRVS PGPVRAVDRV 

       250        260        270        280        290        300 
IEPDLSNATA FLAAAAVTCG EVTVPLWPAE TTQPGDAIRE ILLAMGADVR RDGANLTVRG 

       310        320        330        340        350        360 
PQQLTGIDID LHDVGELTPT VAALAALADG PSHLRGIAHL RGHETDRLAA LAHEINSLGG 

       370        380        390        400        410        420 
NVTETEDGLT IVPADLHGGT WRSYADHRMA TAGAIVGLRV DGIEIEDIGT TAKTLPGFEN 

       430 
LWATMLSASA GTGRKASF

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011115 Genomic DNA. Translation: BAH54646.1.
RefSeqYP_002783591.1. NC_012522.1.

3D structure databases

ProteinModelPortalC1B1F1.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1B1F1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7744118.
GenomeReviewsGene locus ROP_63990 in contig AP011115_GR.
KEGGrop:ROP_63990.
PATRIC23230211. VBIRhoOpa21106_6474.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_RHOOB
AccessionPrimary (citable) accession number: C1B1F1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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