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C1B177 (C1B177_RHOOB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpk EMBL BAH54572.1
Synonyms:glpK HAMAP MF_00186
Ordered Locus Names:ROP_63250
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP]
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding411 – 4155ATP By similarity HAMAP MF_00186

Sites

Binding site141Substrate By similarity HAMAP MF_00186
Binding site181ATP By similarity HAMAP MF_00186
Binding site841Substrate By similarity HAMAP MF_00186
Binding site1361Substrate By similarity HAMAP MF_00186
Binding site2441Substrate By similarity HAMAP MF_00186
Binding site2661ATP By similarity HAMAP MF_00186
Binding site3101ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
C1B177 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 4CC895FE9F0D0CC7

FASTA49754,267
        10         20         30         40         50         60 
MRVIQYIAAI DQGTTSSRCM IFDHDGAVVS VAQKEHEQFF PRAGWVEHDP RQLWINTREV 

        70         80         90        100        110        120 
VASALAKADL TKTDIAAIGI TNQRETAVVW DRNTGEPVYN AIVWQDTRTD ELCTRLGGDE 

       130        140        150        160        170        180 
GPGRYQKRTG LPLSTYFSGP KVRWILDNVD GAREKAEAGE LCFGTIDSWI LWHITEGTHV 

       190        200        210        220        230        240 
TDVTNASRTL LMNLETLDWD PEICADFGIP MSMLPEIRSS SEIYGVGRER GTLPGVPVAG 

       250        260        270        280        290        300 
ILGDQQAATF GQACLSEGEA KNTYGTGNFL LLNTGTTPVH SKHGLLTTVC YKIGDAPAVY 

       310        320        330        340        350        360 
ALEGSVAVTG SLVQWLRDNL GIISSAKDIE DLAKSVDDNG GAYFVPAFSG LFAPRWRPDA 

       370        380        390        400        410        420 
RGAIVGLTRF VNKGHLARAA LEATAYQTRE VIEAMRADSG VELASLKVDG GMVVNETLMQ 

       430        440        450        460        470        480 
FQSDILAVPV IRPVVNETTA LGAAYAAGLA VGFWESEDDI RANWAVDKTW EPGMDEAEST 

       490 
RLYAEWNKAV ERTYDWA

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References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011115 Genomic DNA. Translation: BAH54572.1.
RefSeqYP_002783517.1. NC_012522.1.

3D structure databases

ProteinModelPortalC1B177.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1B177.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7744065.
GenomeReviewsGene locus ROP_63250 in contig AP011115_GR.
KEGGrop:ROP_63250.
PATRIC23230057. VBIRhoOpa21106_6397.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFEPQINP.
ProtClustDBCLSK726606.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1B177_RHOOB
AccessionPrimary (citable) accession number: C1B177
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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