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Protein
Submitted name:

O-acetylhomoserine (Thiol)-lyase

Gene

metY

Organism
Rhodococcus opacus (strain B4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LyaseImported, TransferaseImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciROPA632772:GH0Q-6342-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
O-acetylhomoserine (Thiol)-lyaseImported (EC:2.5.1.49Imported)
Gene namesi
Name:metYImported
Ordered Locus Names:ROP_62960Imported
OrganismiRhodococcus opacus (strain B4)Imported
Taxonomic identifieri632772 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002212 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei209 – 2091N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi632772.ROP_62960.

Structurei

3D structure databases

ProteinModelPortaliC1B148.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the trans-sulfuration enzymes family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2873.
HOGENOMiHOG000246417.
KOiK01740.
OMAiTQADESY.
OrthoDBiEOG67DPN3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1B148-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTENWSFETK QIHAGQTSDA TTKARALPIY QTTSYTFDST DHAAALFGLA
60 70 80 90 100
EPGNIYTRIM NPTQDAVEQR IAALEGGVAA LLLASGQAAE TFAILNLAEA
110 120 130 140 150
GDHIVSSPRL YGGTYNLFHY TLPKLGIEVS FVEDPDDLEQ WKNAIRDNTR
160 170 180 190 200
AFYGETISNP RNDVLDLPGI SGIAHQHGIP LIVDNTVATP YLIRPLEHGA
210 220 230 240 250
DIVVHSATKY LGGHGTAIAG VIVDGGTFDW TQGRHSSFTT PDPSYHGVVY
260 270 280 290 300
SELGPPAYAL KARVQLLRDL GSAISPFNAF LIAQGLETLS LRMERHVSNA
310 320 330 340 350
TAVAQYLEAR PEIVSVGYAG LPSSPWHDRA KQIAPRGAGA IVTFELAGGI
360 370 380 390 400
DAGKKFVNAL TLHSHVANIG DVRSLVIHPA STTHSQLTPE EQAASGVTPG
410 420
LVRLAVGIEG IDDIIADIES GITAAAS
Length:427
Mass (Da):45,414
Last modified:May 26, 2009 - v1
Checksum:iCE2358967995DE11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011115 Genomic DNA. Translation: BAH54543.1.
RefSeqiWP_015890001.1. NC_012522.1.
YP_002783488.1. NC_012522.1.

Genome annotation databases

EnsemblBacteriaiBAH54543; BAH54543; ROP_62960.
KEGGirop:ROP_62960.
PATRICi23229993. VBIRhoOpa21106_6365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011115 Genomic DNA. Translation: BAH54543.1.
RefSeqiWP_015890001.1. NC_012522.1.
YP_002783488.1. NC_012522.1.

3D structure databases

ProteinModelPortaliC1B148.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi632772.ROP_62960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH54543; BAH54543; ROP_62960.
KEGGirop:ROP_62960.
PATRICi23229993. VBIRhoOpa21106_6365.

Phylogenomic databases

eggNOGiCOG2873.
HOGENOMiHOG000246417.
KOiK01740.
OMAiTQADESY.
OrthoDBiEOG67DPN3.

Enzyme and pathway databases

BioCyciROPA632772:GH0Q-6342-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B4Imported.

Entry informationi

Entry nameiC1B148_RHOOB
AccessioniPrimary (citable) accession number: C1B148
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 27, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.