C1B138 (C1B138_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902 EMBL BAH54533.1
Ordered Locus Names:	ROP_62860

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	1084 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1B138 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 1553423FD7BEC5E7	FASTA	1,084	117,830
	10 20 30 40 50 60 MGWGNGPPTW SEMERVLSGR PGRVDPESLY PGDGGDSPAW SRKRGEYRAG RQERSGSTVP 70 80 90 100 110 120 YAELHAHSAF SFLDGASPPE ELVEEAVRLG LEAIALTDHD GFYGVVRFAE AAKELNMRTV 130 140 150 160 170 180 FGSELSLDDA HLLVLARGQE GYRRLSREIA AAHLAGGEKG RLRYDLDRLA DAAGGHWQIL 190 200 210 220 230 240 TGCRKGHVRQ ALADGGPDAA AARLRDLIDR FGADRVTVEL THHGVAEDAE RNACLAELAQ 250 260 270 280 290 300 RHGLRVIAST AAHFAGPPRR RLAMAMAAVR ARQSLDDAAG YLAPAGGAHL RSGEEMAHLF 310 320 330 340 350 360 AAYPDAVRGA AELGLECAFD LRLIAPQLPP FDVPDGHTEA SWLRQLTMDG ARRRYGAPAD 370 380 390 400 410 420 RPEAYRQIEH ELGIITGLNF PGYFLVVHDI VSFCKNNDIL CQGRGSAANS AVCYAIGITN 430 440 450 460 470 480 VDPVRNKLLF ERFLSPERDG PPDIDVDIES DRREEAIQHV YTKYGRQYAA QVANVITYRG 490 500 510 520 530 540 KSSVRDMARA LGFSQGQQDA WSKQVSRWGG IGKEAGTDIP PAVLELAAQI EGFPRHLGIH 550 560 570 580 590 600 SGGMVICDRP IADVCPVEWA RMANRSVLQW DKDDCAAVGL VKFDMLGLGM LSALHYMIDL 610 620 630 640 650 660 VAEHKGIEVD LAQLDLSEEA VYEMLQRADS VGVFQVESRA QMATLPRLKP RNFYDLVVEV 670 680 690 700 710 720 ALIRPGPIQG GSVHPYIRRR NKLEPVTYDH PSLEKALKRT LGVPLFQEQL MQMAVDVAGF 730 740 750 760 770 780 SPAEADQLRR AMGSKRSPEK MERLRGRFYQ GMRELHGIGG DVADRIYEKL FAFANFGFPE 790 800 810 820 830 840 SHSQSFAALV FYSSWFKLHH PAAFCAGLLR AQPMGFYSPQ SLVADARRHG VRVHGADVNA 850 860 870 880 890 900 SLAHATVEAG GTEVRLGLGE VRHIGTALAE RIVDSRGDGG PYTSFLDLTG RVELSTAQAE 910 920 930 940 950 960 SLATAGALDS FGLSRREALW AAGAAAGERR DRLPGIGAST RAPTLPGMSD LELAAADVWA 970 980 990 1000 1010 1020 TGVSPDTYPT EFLRPQLDAL GVIPAAHLLD VPDGDRVLVG GAVTHRQRPA TAAGVTFINL 1030 1040 1050 1060 1070 1080 EDETGMVNVV CSVGLWAKYR KLANTAPALL VRGKVQNAEG AVTVVADRLQ LMDLRVSAKS RDFR

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH54533.1.
RefSeq	YP_002783478.1. NC_012522.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1B138.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7742712.
GenomeReviews	Gene locus ROP_62860 in contig AP011115_GR.
KEGG	rop:ROP_62860.
PATRIC	23229973. VBIRhoOpa21106_6355.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EQPAIRL.
ProtClustDB	PRK05672.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1B138_RHOOB

Accession

Primary (citable) accession number: C1B138

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)