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C1B066 (C1B066_RHOOB) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL BAH54487.1
Ordered Locus Names:ROP_62400 EMBL BAH54487.1
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP] EMBL BAH54487.1
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site581Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2871Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1561Substrate By similarity HAMAP-Rule MF_01201
Binding site3351Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue581N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C1B066 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: F3B90705D1A02D74

FASTA40041,837
        10         20         30         40         50         60 
MTLAEAVPAD DHGHSEPAAP AQAAAPQAEA VVDLDAIAHN VRILRDSARG AAMMAVVKAD 

        70         80         90        100        110        120 
GYNHGAVAVA RAALAAGASE LGVTTVSEAL TLRRAGIDAP VLAWLHTVDA DFAPAIAADV 

       130        140        150        160        170        180 
ELGVSSPRHL AAVVAAARRV GTPAIVTMKV DTGLNRNGVA PDELAQVLVD LARAQAEGSV 

       190        200        210        220        230        240 
RLRGIFSHLA HADEPHHAWI DSQRDRLVDA IADAKRHGLV PEVVHLSNSA ATLTRPDLRF 

       250        260        270        280        290        300 
DMVRPGIAIY GLSPVPELGQ FGLRPAMTLR SRVALVKKVA AGEGVSYGHQ WVAPRDTTVA 

       310        320        330        340        350        360 
LLPLGYADGL PRSLSGRFEV QLGAERRPGI GRVCMDQVVV DLGPDGGGVR EGDTAVFFGN 

       370        380        390        400 
GDLGEPIAQE WADKLDTIHY EVVTGVRGRT VRTYVGGTGT 

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B4 EMBL BAH54487.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP011115 Genomic DNA. Translation: BAH54487.1.
RefSeqYP_002783432.1. NC_012522.1.

3D structure databases

ProteinModelPortalC1B066.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING632772.ROP_62400.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAH54487; BAH54487; ROP_62400.
GeneID7742673.
KEGGrop:ROP_62400.
PATRIC23229879. VBIRhoOpa21106_6308.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAGHTWTAQ.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycROPA632772:GH0Q-6286-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC1B066_RHOOB
AccessionPrimary (citable) accession number: C1B066
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)