Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C1AX87

- DNLI_RHOOB

UniProt

C1AX87 - DNLI_RHOOB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable DNA ligase

Gene

lig

Organism
Rhodococcus opacus (strain B4)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Divalent metal cations.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei210 – 2101ATPUniRule annotation
Active sitei212 – 2121N6-AMP-lysine intermediateUniRule annotation
Binding sitei217 – 2171ATPUniRule annotation
Binding sitei232 – 2321ATPUniRule annotation
Binding sitei261 – 2611ATPUniRule annotation
Binding sitei296 – 2961ATPUniRule annotation
Binding sitei367 – 3671ATPUniRule annotation
Binding sitei373 – 3731ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. DNA biosynthetic process Source: InterPro
  4. DNA ligation involved in DNA repair Source: InterPro
  5. DNA recombination Source: UniProtKB-HAMAP
  6. DNA replication Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciROPA632772:GH0Q-1364-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]UniRule annotation
Gene namesi
Name:ligUniRule annotation
Ordered Locus Names:ROP_13440
OrganismiRhodococcus opacus (strain B4)
Taxonomic identifieri632772 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002212: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 503503Probable DNA ligasePRO_1000134731Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi632772.ROP_13440.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK01971.
OMAiRKVKPVH.
OrthoDBiEOG6Q8HXT.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C1AX87-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLFSQIVATS RDVGATRSRK VKVATLREAL TRLEQAEVEP VVAWLSGELR
60 70 80 90 100
QGRIGIGWRT VADIPATPAD VAAVTVSEVD GTISAVAEVS GSGSAARRRE
110 120 130 140 150
LLADLFARTT ADERDFLLRL LTGDLRQGAL EGVMTDAIAA AADLPIEPVR
160 170 180 190 200
RAFMLSGRLP ATAVAAFDGG VDALTAFRLE VGRPVRPMLA SPAESLADAW
210 220 230 240 250
SELGGDVSVE YKLDGARIQV HRNGDEVRIF TRTLREITGS VPELVALVAR
260 270 280 290 300
LPCTSAVFDG ETLALTDSGR PRPFQETMSR FGAESARDLL LHPYFFDCLH
310 320 330 340 350
LDGVDLLDSP LEERLKALER VAPQHRIPGL IRPDSEGAAT HFDDALAAGH
360 370 380 390 400
EGVMVKSLTA PYAAGRRGRA WQKVKPEHTL DLVVLGAEWG YGRRTGYLSN
410 420 430 440 450
LHLGARDPDG GAPIMVGKTF KGLTDALLQW QTDEFPRHER ARDDHTVYLH
460 470 480 490 500
PDLVVEIELD GVQVSTRYPG GLALRFARVL RYRPDKTAAD ADTIDAVRSL

LPG
Length:503
Mass (Da):54,564
Last modified:May 26, 2009 - v1
Checksum:iE47CF1599977069D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011115 Genomic DNA. Translation: BAH49591.1.
RefSeqiYP_002778536.1. NC_012522.1.

Genome annotation databases

EnsemblBacteriaiBAH49591; BAH49591; ROP_13440.
GeneIDi7747097.
KEGGirop:ROP_13440.
PATRICi23219891. VBIRhoOpa21106_1344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011115 Genomic DNA. Translation: BAH49591.1 .
RefSeqi YP_002778536.1. NC_012522.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 632772.ROP_13440.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAH49591 ; BAH49591 ; ROP_13440 .
GeneIDi 7747097.
KEGGi rop:ROP_13440.
PATRICi 23219891. VBIRhoOpa21106_1344.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036008.
KOi K01971.
OMAi RKVKPVH.
OrthoDBi EOG6Q8HXT.

Enzyme and pathway databases

BioCyci ROPA632772:GH0Q-1364-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B4.

Entry informationi

Entry nameiDNLI_RHOOB
AccessioniPrimary (citable) accession number: C1AX87
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3