C1AVN8 (C1AVN8_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inositol 2-dehydrogenase HAMAP MF_01671
EC=1.1.1.18 HAMAP MF_01671

Alternative name(s):
Myo-inositol 2-dehydrogenase HAMAP MF_01671

Gene names

Name:	idh EMBL BAH49318.1
Synonyms:	iolG HAMAP MF_01671
Ordered Locus Names:	ROP_10710

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	356 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP MF_01671
Catalytic activity	Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. SAAS SAAS000683 HAMAP MF_01671
Subunit structure	Homotetramer By similarity. HAMAP MF_01671 SAAS SAAS000683
Sequence similarities	Belongs to the gfo/idh/mocA family. HAMAP MF_01671

Ontologies

Keywords
Ligand	NAD SAAS SAAS000683 HAMAP MF_01671
Molecular function	Oxidoreductase SAAS SAAS000683 HAMAP MF_01671 EMBL BAH49318.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	inositol 2-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1AVN8 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 71F934875E1B880C	FASTA	356	37,894
	10 20 30 40 50 60 MSKSSTELRI AVLGVGMMGA DHVARITDRI KGATVAVVND YFIEKAEEIA AGIPGCRAVN 70 80 90 100 110 120 DPLDAIADPG VDAVVLATPG PTHEKQLLAC LEHGKPVMCE KPLTTDVATS LEIVKREAEL 130 140 150 160 170 180 GKKLIQVGFM RRFDHEYEQL KSLIDDGTFG QVLLAHCVHR NPVVPPGFDS SMIVKDSLVH 190 200 210 220 230 240 EVDVTRFLFD EEITSVQILR PAANPGAPEG LQDPQIAFFT TESGRHVDVE VFVTTGVAYE 250 260 270 280 290 300 VRTEIVAEKG SAFIGLDVGL VRKYGTGAGN GRSGAGAWGG EITPSFKERF GQAYDAEIQR 310 320 330 340 350 WVNAARTGAE TGNYVDGPGA WDGYAAAAVC AAGVQSLETG ERVAVDMVDR SSIPGA

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH49318.1.
RefSeq	YP_002778263.1. NC_012522.1.
3D structure databases
ProteinModelPortal	C1AVN8.
ModBase	Search...
Protein-protein interaction databases
STRING	C1AVN8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7741765.
GenomeReviews	Gene locus ROP_10710 in contig AP011115_GR.
KEGG	rop:ROP_10710.
PATRIC	23219329. VBIRhoOpa21106_1074.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	RTEVVGE.
ProtClustDB	CLSK956652.
Family and domain databases
HAMAP	MF_01671. IolG. [Tree]
InterPro	IPR023794. MI/DCI_dehydrogenase. IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR004104. OxRdtase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00010.
PANTHER	PTHR22604:SF7. PTHR22604:SF7. 1 hit.
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF02894. GFO_IDH_MocA_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1AVN8_RHOOB

Accession

Primary (citable) accession number: C1AVN8

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)