C1AVM5 (C1AVM5_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Shikimate dehydrogenase HAMAP MF_00222
EC=1.1.1.25 HAMAP MF_00222

Gene names

Name:	aroE HAMAP MF_00222 EMBL BAH49305.1
Ordered Locus Names:	ROP_10580

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Shikimate + NADP+ = 3-dehydroshikimate + NADPH. HAMAP MF_00222
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_00222
Sequence similarities	Belongs to the shikimate dehydrogenase family. HAMAP MF_00222

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00222
Ligand	NADP HAMAP MF_00222
Molecular function	Oxidoreductase HAMAP MF_00222 SAAS SAAS022893 EMBL BAH49305.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	143 – 147	5	NADP By similarity HAMAP MF_00222
Sites
	Active site	83	1	Proton acceptor By similarity HAMAP MF_00222

Sequences

	Sequence		Length	Mass (Da)
	C1AVM5 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: B3805BE5F054A039	FASTA	304	31,747
	10 20 30 40 50 60 MTSRDLDAPN ARPSYLCGLI GTGISKSLTP PLHEAEGRAQ GVGYVYRILD LDTLGMGVEG 70 80 90 100 110 120 LPRLLDAATL LGFNGLNITH PCKQAIIPLL DDLSDDARKL GAVNTVHIDG GRLVGHNTDW 130 140 150 160 170 180 SGFARNMDEG LEGAPMNRVV QLGAGGAGAA VAYAALTRGV GHFTIIDADV ARSTALRDSL 190 200 210 220 230 240 AGLFPDREIE AGDLAAVPAA VGAAQGLIHA TPLGMAAHPG MALDAALLRP DLWVADVVYR 250 260 270 280 290 300 PAETELLRRA REIGARTLSG IGMTIGQAVD SFRIFTGLEP DAQRMREYMG LLLQAEDAAA LAGA

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH49305.1.
RefSeq	YP_002778250.1. NC_012522.1.
3D structure databases
ProteinModelPortal	C1AVM5.
ModBase	Search...
Protein-protein interaction databases
STRING	C1AVM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7744144.
GenomeReviews	Gene locus ROP_10580 in contig AP011115_GR.
KEGG	rop:ROP_10580.
PATRIC	23219303. VBIRhoOpa21106_1061.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	HEHEGDA.
ProtClustDB	PRK12549.
Family and domain databases
HAMAP	MF_00222. Shikimate_DH_AroE. [Tree]
InterPro	IPR016040. NAD(P)-bd_dom. IPR013708. Shikimate_DH-bd_N. IPR022893. Shikimate_quinate_DH. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00014.
Pfam	PF08501. Shikimate_dh_N. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1AVM5_RHOOB

Accession

Primary (citable) accession number: C1AVM5

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)