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C1AVI9 (C1AVI9_RHOOB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Gamma-glutamyl phosphate reductase HAMAP MF_00412
Short name=GPR HAMAP MF_00412
EC=1.2.1.41 HAMAP MF_00412
Alternative name(s):
Glutamate-5-semialdehyde dehydrogenase HAMAP MF_00412
Glutamyl-gamma-semialdehyde dehydrogenase HAMAP MF_00412
Gene names
Name:proA HAMAP MF_00412 EMBL BAH49269.1
Ordered Locus Names:ROP_10220
OrganismRhodococcus opacus (strain B4) [Complete proteome] [HAMAP]
Taxonomic identifier632772 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate By similarity. HAMAP MF_00412 SAAS SAAS020593

Catalytic activity

L-glutamate 5-semialdehyde + phosphate + NADP+ = L-glutamyl 5-phosphate + NADPH. HAMAP MF_00412 SAAS SAAS020593

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2. HAMAP MF_00412 SAAS SAAS020593

Subcellular location

Cytoplasm By similarity HAMAP MF_00412 SAAS SAAS020593.

Sequence similarities

Belongs to the gamma-glutamyl phosphate reductase family. HAMAP MF_00412

Sequences

Sequence LengthMass (Da)Tools
C1AVI9 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: A548C3032104DF10

FASTA42644,136
        10         20         30         40         50         60 
MTAVTSTSSA GATVDTREAV HAAARRARTA SRVLALLTTA QKDAALHAAA DAVLAASTDI 

        70         80         90        100        110        120 
LAANAADIEA ARASGTEESL LDRLRLTAER IGGIASGLRQ VAGLPDPVGE VVRGSTLPNG 

       130        140        150        160        170        180 
LELRQLRVPL GVVGMVYEAR PNVTVDAFGL ALKSGNAALL RGSSSAAKSN AALVVALRTS 

       190        200        210        220        230        240 
LAAQELPADA VQLLPSEDRS SVTHLIQARG LVDVVIPRGG AGLISAVVRD ATVPTIETGV 

       250        260        270        280        290        300 
GNCHVYVHAA ADLKMAERVL LNSKTRRPSV CNTAETVLID AAIAETAVPK LLQALQMHSV 

       310        320        330        340        350        360 
TVHGDLPGLV PATESDWSEE YLTLDVALKV VDDLNAAVEH IDRYGTGHTE AIVTSDLAAA 

       370        380        390        400        410        420 
REFTARVDAA AVMVNASTAF TDGEQIGFGA EIGISTQKLH ARGPMGLPEL TSTKWIVWGD 


GHTRPV

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011115 Genomic DNA. Translation: BAH49269.1.
RefSeqYP_002778214.1. NC_012522.1.

3D structure databases

ProteinModelPortalC1AVI9.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1AVI9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7744129.
GenomeReviewsGene locus ROP_10220 in contig AP011115_GR.
KEGGrop:ROP_10220.
PATRIC23219227. VBIRhoOpa21106_1023.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQYPAACN.
ProtClustDBPRK00197.

Family and domain databases

HAMAPMF_00412. ProA.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR000965. G-glutamylP_reductase.
IPR020593. G-glutamylP_reductase_CS.
IPR012134. Glu-5-SA_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 2 hits.
KOK00147.
PANTHERPTHR11063:SF1. GSA_DH. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
PIRSFPIRSF000151. GPR. 1 hit.
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR00407. ProA. 1 hit.
PROSITEPS01223. PROA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1AVI9_RHOOB
AccessionPrimary (citable) accession number: C1AVI9
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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