C1AU72 (C1AU72_RHOOB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Name:	metF EMBL BAH49080.1
Ordered Locus Names:	ROP_08330

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Pathway	One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU004255
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004255
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862 EMBL BAH49080.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1AU72 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 2F24ADE3CFBD298E	FASTA	321	34,895
	10 20 30 40 50 60 MTRTPSIVDR IRSSGDGRVP FSVEFSPPRD EAAEARLWRA VREFERMGPA FVSMTYGAGG 70 80 90 100 110 120 STRDRTVRVT GQLAEETTLL PVAHLTAVSH SVDELRSMVG AYADRGISNI LVLRGDPPGD 130 140 150 160 170 180 PLGEWEKHPQ GVEYAEELVR LVRDLGDFHV GVASFPEGHY RAPDLAHDTR YLVSKLRAGA 190 200 210 220 230 240 EYSITQMFFD VDDYLRLRDR VTAYDPEQGA KPIIPEIMPI TSLGSVRRML ELSGSSLPAH 250 260 270 280 290 300 LEKRLAAAAG DGPEENRAAV REIGIDLATE MSERLIAEGA PGLHFITLNF ARATSEVLAR 310 320 LGDKVGSGVA DPAPVTPAPV S

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH49080.1.
RefSeq	YP_002778025.1. NC_012522.1.
3D structure databases
ProteinModelPortal	C1AU72.
ModBase	Search...
Protein-protein interaction databases
STRING	C1AU72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7747900.
GenomeReviews	Gene locus ROP_08330 in contig AP011115_GR.
KEGG	rop:ROP_08330.
PATRIC	23218839. VBIRhoOpa21106_0832.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITQMFFD.
ProtClustDB	CLSK758165.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1AU72_RHOOB

Accession

Primary (citable) accession number: C1AU72

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)