C1ASX3 (KCY_RHOOB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	ROP_06580

Organism

Rhodococcus opacus (strain B4) [Complete proteome] [HAMAP]

Taxonomic identifier

632772 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 229	229	Cytidylate kinase HAMAP MF_00238		PRO_1000125295
Regions
	Nucleotide binding	12 – 20	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	C1ASX3 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 288A691F136B0069	FASTA	229	24,051
	10 20 30 40 50 60 MSTSSLIVAM DGPSGTGKSS VSRMLARRLG ARYLDTGAMY RIATLHVLRK GVDLADPDAI 70 80 90 100 110 120 ADATVGLPWS IGTDPAGEQV LLDGEDVGEE IRGDAVTKAV SAVSAVPAVR ELLVAAQRRL 130 140 150 160 170 180 ACEAGRIVVE GRDIGTVVLP DADVKIYLTA SAEARAQRRN AQNLAEGRGD DFAAVLADVQ 190 200 210 220 RRDHLDSTRA VSPLRPADDS VLVDTSELGI DDVIGRLLLV VSERSGVGQ

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: B4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP011115 Genomic DNA. Translation: BAH48905.1.
RefSeq	YP_002777850.1. NC_012522.1.
3D structure databases
ProteinModelPortal	C1ASX3.
ModBase	Search...
Protein-protein interaction databases
STRING	C1ASX3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7741524.
GenomeReviews	Gene locus ROP_06580 in contig AP011115_GR.
KEGG	rop:ROP_06580.
PATRIC	23218475. VBIRhoOpa21106_0654.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DIGTVIC.
ProtClustDB	PRK00023.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_RHOOB

Accession

Primary (citable) accession number: C1ASX3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program