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Protein

Putative pterin-4-alpha-carbinolamine dehydratase

Gene

JTY_1194

Organism
Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciMBOV561275:GHDN-1210-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pterin-4-alpha-carbinolamine dehydrataseUniRule annotation (EC:4.2.1.96UniRule annotation)
Short name:
PHSUniRule annotation
Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydrataseUniRule annotation
Pterin carbinolamine dehydrataseUniRule annotation
Short name:
PCDUniRule annotation
Gene namesi
Ordered Locus Names:JTY_1194
OrganismiMycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
Taxonomic identifieri561275 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9494Putative pterin-4-alpha-carbinolamine dehydratasePRO_1000192918Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC1AMF4.
SMRiC1AMF4. Positions 26-92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pterin-4-alpha-carbinolamine dehydratase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000007680.
KOiK01724.
OMAiFALVTHS.
OrthoDBiEOG6S52NH.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.

Sequencei

Sequence statusi: Complete.

C1AMF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVLTDEQVD AALHDLNGWQ RAGGVLRRSI KFPTFMAGID AVRRVAERAE
60 70 80 90
EVNHHPDIDI RWRTVTFALV THAVGGITEN DIAMAHDIDA MFGA
Length:94
Mass (Da):10,380
Last modified:May 26, 2009 - v1
Checksum:i21F1A514995CE65A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010918 Genomic DNA. Translation: BAH25483.1.
RefSeqiWP_003406082.1. NZ_CP014566.1.

Genome annotation databases

EnsemblBacteriaiBAH25483; BAH25483; JTY_1194.
KEGGimbt:JTY_1194.
PATRICi18021851. VBIMycBov85238_1310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010918 Genomic DNA. Translation: BAH25483.1.
RefSeqiWP_003406082.1. NZ_CP014566.1.

3D structure databases

ProteinModelPortaliC1AMF4.
SMRiC1AMF4. Positions 26-92.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH25483; BAH25483; JTY_1194.
KEGGimbt:JTY_1194.
PATRICi18021851. VBIMycBov85238_1310.

Phylogenomic databases

HOGENOMiHOG000007680.
KOiK01724.
OMAiFALVTHS.
OrthoDBiEOG6S52NH.

Enzyme and pathway databases

BioCyciMBOV561275:GHDN-1210-MONOMER.

Family and domain databases

Gene3Di3.30.1360.20. 1 hit.
HAMAPiMF_00434. Pterin_4_alpha.
InterProiIPR001533. Trans/pterin_deHydtase.
[Graphical view]
PANTHERiPTHR12599. PTHR12599. 1 hit.
PfamiPF01329. Pterin_4a. 1 hit.
[Graphical view]
SUPFAMiSSF55248. SSF55248. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains."
    Seki M., Honda I., Fujita I., Yano I., Yamamoto S., Koyama A.
    Vaccine 27:1710-1716(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BCG / Tokyo 172 / ATCC 35737 / TMC 1019.

Entry informationi

Entry nameiPHS_MYCBT
AccessioniPrimary (citable) accession number: C1AMF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 26, 2009
Last modified: July 6, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.