C1AH88 (C1AH88_MYCBT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540

Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540

Gene names

Name:	add_1 EMBL BAH27617.1
Synonyms:	add1 HAMAP MF_00540, add_2 EMBL BAH27636.1, add_3 EMBL BAH27655.1
Ordered Locus Names:	JTY_3339, JTY_3359, JTY_3379

Organism

Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019) [Complete proteome] [HAMAP] EMBL BAH27617.1

Taxonomic identifier

561275 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Cofactor	Binds 1 zinc ion per subunit By similarity. SAAS SAAS006330 HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS006330 HAMAP MF_00540
Ligand	Metal-binding SAAS SAAS006330 HAMAP MF_00540 Zinc SAAS SAAS006330 HAMAP MF_00540
Molecular function	Hydrolase SAAS SAAS006330 HAMAP MF_00540 EMBL BAH27617.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1AH88 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: C034CDCEC377BB29	FASTA	365	39,743
	10 20 30 40 50 60 MTAAPTLQTI RLAPKALLHD HLDGGLRPAT VLDIAGQVGY DDLPATDVDA LASWFRTQSH 70 80 90 100 110 120 SGSLERYLEP FSHTVAVMQT PEALYRVAFE CAQDLAADSV VYAEVRFAPE LHISCGLSFD 130 140 150 160 170 180 DVVDTVLTGF AAGEKACAAD GQPITVRCLV TAMRHAAMSR EIAELAIRFR DKGVVGFDIA 190 200 210 220 230 240 GAEAGHPPTR HLDAFEYMRD HNARFTIHAG EAFGLPSIHE AIAFCGADRL GHGVRIVDDI 250 260 270 280 290 300 DVDADGGFQL GRLAAILRDK RIPLELCPSS NVQTGAVASI AEHPFDLLAR ARFRVTVNTD 310 320 330 340 350 360 NRLMSDTSMS LEMHRLVEAF GYGWSDLARF TVNAMKSAFI PFDQRLAIID EVIKPRFAAL MGHSE

References

[1]

"Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains." Seki M., Honda I., Fujita I., Yano I., Yamamoto S., Koyama A. Vaccine 27:1710-1716(2009) [PubMed: 19200449] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010918 Genomic DNA. Translation: BAH27617.1. AP010918 Genomic DNA. Translation: BAH27636.1. AP010918 Genomic DNA. Translation: BAH27655.1.
RefSeq	YP_002646385.1. NC_012207.1. YP_002646404.1. NC_012207.1. YP_002646423.1. NC_012207.1.
3D structure databases
ProteinModelPortal	C1AH88.
ModBase	Search...
Protein-protein interaction databases
STRING	C1AH88.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000088187; EBMYCP00000084709; EBMYCG00000090339. EBMYCT00000091111; EBMYCP00000084631; EBMYCG00000091669. EBMYCT00000091202; EBMYCP00000086604; EBMYCG00000089031.
GeneID	7560907. 7560912. 7560917.
GenomeReviews	Gene locus JTY_3339 in contig AP010918_GR. Gene locus JTY_3359 in contig AP010918_GR. Gene locus JTY_3379 in contig AP010918_GR.
KEGG	mbt:JTY_3339. mbt:JTY_3359. mbt:JTY_3379.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016615.
OMA	PYYMAMN.
ProtClustDB	PRK09358.
Family and domain databases
HAMAP	MF_00540. A_deaminase. [Tree]
InterPro	IPR001365. A/AMP_deaminase_dom. IPR006330. A_deaminase. [Graphical view]
KO	K01488.
PANTHER	PTHR11409:SF21. PTHR11409:SF21. 1 hit.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. Aden_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C1AH88_MYCBT

Accession

Primary (citable) accession number: C1AH88

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)