C1AFM6 (C1AFM6_MYCBT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative dihydrofolate reductase EMBL BAH27055.1
EC=1.5.1.3 EMBL BAH27055.1

Gene names

Name:	dfrA EMBL BAH27055.1
Ordered Locus Names:	JTY_2774

Organism

Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019) [Complete proteome] [HAMAP] EMBL BAH27055.1

Taxonomic identifier

561275 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL BAH27055.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1AFM6 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: F17C038F1B773797	FASTA	159	17,640
	10 20 30 40 50 60 MVGLIWAQAT SGVIGRGGDI PWRLPEDQAH FREITMGHTI VMGRRTWDSL PAKVRPLPGR 70 80 90 100 110 120 RNVVLSRQAD FMASGAEVVG SLEEALTSPE TWVIGGGQVY ALALPYATRC EVTEVDIGLP 130 140 150 REAGDALAPV LDETWRGETG EWRFSRSGLR YRLYSYHRS

References

[1]

"Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains." Seki M., Honda I., Fujita I., Yano I., Yamamoto S., Koyama A. Vaccine 27:1710-1716(2009) [PubMed: 19200449] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP010918 Genomic DNA. Translation: BAH27055.1.
RefSeq	YP_002645823.1. NC_012207.1.
3D structure databases
ProteinModelPortal	C1AFM6.
SMR	C1AFM6. Positions 1-159.
ModBase	Search...
Protein-protein interaction databases
STRING	C1AFM6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000090087; EBMYCP00000084647; EBMYCG00000088504.
GeneID	7562334.
GenomeReviews	Gene locus JTY_2774 in contig AP010918_GR.
KEGG	mbt:JTY_2774.
PATRIC	18025319. VBIMycBov85238_3025.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017411.
OMA	HATRCEV.
ProtClustDB	CLSK792062.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1AFM6_MYCBT

Accession

Primary (citable) accession number: C1AFM6

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)