ID   C1A7K0_GEMAT            Unreviewed;       494 AA.
AC   C1A7K0;
DT   26-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   26-MAY-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:BAH38210.1};
GN   OrderedLocusNames=GAU_1168 {ECO:0000313|EMBL:BAH38210.1};
OS   Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC
OS   100505).
OC   Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC   Gemmatimonadaceae; Gemmatimonas.
OX   NCBI_TaxID=379066 {ECO:0000313|EMBL:BAH38210.1, ECO:0000313|Proteomes:UP000002209};
RN   [1] {ECO:0000313|Proteomes:UP000002209}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T-27 / DSM 14586 / JCM 11422 / NBRC 100505
RC   {ECO:0000313|Proteomes:UP000002209};
RA   Takasaki K., Ichikawa N., Miura H., Matsushita S., Watanabe Y., Oguchi A.,
RA   Ankai A., Yashiro I., Takahashi M., Terui Y., Fukui S., Yokoyama H.,
RA   Tanikawa S., Hanada S., Kamagata Y., Fujita N.;
RT   "Complete genome sequence of Gemmatimonas aurantiaca T-27 that represents a
RT   novel phylum Gemmatimonadetes.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; AP009153; BAH38210.1; -; Genomic_DNA.
DR   RefSeq; WP_012682657.1; NC_012489.1.
DR   AlphaFoldDB; C1A7K0; -.
DR   STRING; 379066.GAU_1168; -.
DR   KEGG; gau:GAU_1168; -.
DR   eggNOG; COG1012; Bacteria.
DR   HOGENOM; CLU_005391_0_0_0; -.
DR   OrthoDB; 9762913at2; -.
DR   Proteomes; UP000002209; Chromosome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR   CDD; cd07131; ALDH_AldH-CAJ73105; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; ALDH-like; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003345};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002209}.
FT   DOMAIN          12..476
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   ACT_SITE        249
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ   SEQUENCE   494 AA;  53061 MW;  FFB87CA3085DBFBB CRC64;
     MTTFKNFIGG QWVAPSTDAY FDNRNPANQD DLIGRFPASG VADVEAAVAS ALRGFERWKR
     TPAPARGDVL RRVGDLLASR KEELADIMTR EMGKPLAETR GDVQEGIDTA YYAATEGRRL
     FGHTVPSELA NKWAMSMRRP IGVCGLITPF NFPLAIPTWK AFPALLCGNS VILKPAEDVP
     HTATVLVEIL LEAGLPPEVI QLVHGMGEVV GKALVEHPQV PVISFTGSTE TGRFVGETCG
     RMHKRLSLEM GGKNAQIVLD DADLDLALDG VLWGAFGTTG QRCTATSRLI VQSGVHDALV
     ARLAERAKAL RLGDGRVAGT DVGPLVSEAA REKVERYIGI GKEQGATLVC GGERATGGAL
     DKGFFFQPTI FSGVTAGSRL DQEEIFGPVL SVIRVESVEE AFAVNNGVRY GLSSAVYTGN
     VNVAFRALQD LDNGITYINA PTIGAEAHMP FGGVKETGNG HREGGWEVYE FYSETKVGYV
     DYSGALQRAQ IDNY
//