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C1A1L4 (C1A1L4_RHOE4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456 EMBL BAH34499.1
Ordered Locus Names:RER_37910
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. SAAS SAAS011529 HAMAP MF_00456

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain279 – 35375PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
C1A1L4 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 3B0BB60A9F9929F6

FASTA36737,690
        10         20         30         40         50         60 
MLGSTRESIA SAHSIVVKIG SSALTSLVAG LDTHRLDLLA DAIETRMRAG SDVVVVSSGA 

        70         80         90        100        110        120 
VGAGLAPLGL TKRPRDLATK QAAASVGQLA LAHAWGTSFA RYGRTVGQVL LTADDIARRT 

       130        140        150        160        170        180 
QHRNAQRTLD RLRALHAVAI VNENDTVATT ELRFGDNDRL AALVAHLVGA DALILLSDVD 

       190        200        210        220        230        240 
GLYDGDPRKG DATLIPEVNS PEDLDGVVAG SGGALGTGGM ASKLSAARLA ADSGVPVLLA 

       250        260        270        280        290        300 
AASDAAQALS GADVGTAFAP RPTRLSARRF WVRHAADTSG DLHLDEGAVR AVVSKRRSLL 

       310        320        330        340        350        360 
SAGIVGVSGD FHAGDVVSLM GPGEKPVARG VVAFDATEIE EILGRSTADL PADMQRPVVH 


ADDLVAL

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH34499.1.
RefSeqYP_002767238.1. NC_012490.1.

3D structure databases

ProteinModelPortalC1A1L4.
ModBaseSearch...

Protein-protein interaction databases

STRINGC1A1L4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7712742.
GenomeReviewsGene locus RER_37910 in contig AP008957_GR.
KEGGrer:RER_37910.
PATRIC23194081. VBIRhoEry66701_4315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC1A1L4_RHOE4
AccessionPrimary (citable) accession number: C1A1L4
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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