C1A0Z2 (C1A0Z2_RHOE4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Name:	metF EMBL BAH34277.1
Ordered Locus Names:	RER_35690

Organism

Rhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]

Taxonomic identifier

234621 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Pathway	One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU004255
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004255
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862 EMBL BAH34277.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW methionine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1A0Z2 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 2EFD1C3FCC2C0FF7	FASTA	329	36,011
	10 20 30 40 50 60 MTFDPVRGRS SEGWATRTPS IVDRIASSTG SRIPFSVEFS PPRDADAEAR LWRAVRTFER 70 80 90 100 110 120 LGPAFVSMTY GAGGSTRDRT VRVTGELAEE TTLLPVAHLT AVSHSTEELR AMVGAYADRG 130 140 150 160 170 180 ISNILVLRGD PPGDPLGEWK KHPEGVEYAE ELVRMVRDLG DFHVGVASFP EGHYRAPDLA 190 200 210 220 230 240 YDTKYLVSKL RAGAEYSITQ MFFDVEDYLR LRDRVSAYDA EQGAKPIIPE IMPVTSLRSV 250 260 270 280 290 300 RRMLELSGSS LPPALERRFD AAAGSGPEEN RAAVRELGID LATEMGERLI AEGAPCLHFI 310 320 TLNFARATSE VLERLGLTPD TSVGTAQAV

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008957 Genomic DNA. Translation: BAH34277.1.
RefSeq	YP_002767016.1. NC_012490.1.
3D structure databases
ProteinModelPortal	C1A0Z2.
ModBase	Search...
Protein-protein interaction databases
STRING	C1A0Z2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7712615.
GenomeReviews	Gene locus RER_35690 in contig AP008957_GR.
KEGG	rer:RER_35690.
PATRIC	23193612. VBIRhoEry66701_4084.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITQMFFD.
ProtClustDB	CLSK758165.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1A0Z2_RHOE4

Accession

Primary (citable) accession number: C1A0Z2

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)