Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamate decarboxylase

Gene

RER_35380

Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciRERY234621:GHDE-3579-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:RER_35380Imported
OrganismiRhodococcus erythropolis (strain PR4 / NBRC 100887)Imported
Taxonomic identifieri234621 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000002204 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi234621.RER_35380.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C1A0W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEPRRSDHT DYVAVNPIFS RPGEDSVASK YTLEPDGMLP ETAYQIVHDE
60 70 80 90 100
TMLDGNARLN LATFVSTWMD DHATKLYTES FDKNMIDKDE YPQTAAIETY
110 120 130 140 150
CWRILADLWH SPSPKDAIGT STIGSSEACM LGGLAMKRRW QHARKAAGKS
160 170 180 190 200
TEKPNLIMSS AVQVCWEKFC NYWDVEARYV PISEEHRTLD GHDLDKYVDE
210 220 230 240 250
NTIGVIAIMG VTYTGMYEPV LEISKALDAI QEKTGLDVPI HVDGASGAMI
260 270 280 290 300
APFLQPELEW DFRLPRVHSI NTSAHKYGLV YPGLGWVVWR SQDLLPDDLV
310 320 330 340 350
FKVSYLGGSM PTFALNFSRP GAQVILQFYL FLRLGHDGYR AIQQSSQDVA
360 370 380 390 400
KFLAEGIGKL DAFELWNDGS DIPVFAWRLA EGHTSNWTLY DLSDRLRGKG
410 420 430 440 450
WLVPAYPMPD DLADLTVQRI VVRNGLSMDL AANLLRIIEE ETAFLDELDS
460
PMPRPRVTEG FHH
Length:463
Mass (Da):52,181
Last modified:May 26, 2009 - v1
Checksum:i35D846558142E709
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH34246.1.
RefSeqiWP_020908066.1. NC_012490.1.
YP_002766985.1. NC_012490.1.

Genome annotation databases

EnsemblBacteriaiBAH34246; BAH34246; RER_35380.
GeneIDi7712601.
KEGGirer:RER_35380.
PATRICi23193552. VBIRhoEry66701_4054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008957 Genomic DNA. Translation: BAH34246.1.
RefSeqiWP_020908066.1. NC_012490.1.
YP_002766985.1. NC_012490.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi234621.RER_35380.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH34246; BAH34246; RER_35380.
GeneIDi7712601.
KEGGirer:RER_35380.
PATRICi23193552. VBIRhoEry66701_4054.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciRERY234621:GHDE-3579-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
    Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.
  2. "Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4."
    Sekine M., Tanikawa S., Omata S., Saito M., Fujisawa T., Tsukatani N., Tajima T., Sekigawa T., Kosugi H., Matsuo Y., Nishiko R., Imamura K., Ito M., Narita H., Tago S., Fujita N., Harayama S.
    Environ. Microbiol. 8:334-346(2006)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PR4 / NBRC 100887Imported.

Entry informationi

Entry nameiC1A0W1_RHOE4
AccessioniPrimary (citable) accession number: C1A0W1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: May 27, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.