C1A0S1 (C1A0S1_RHOE4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative 3-hydroxy-3-methylglutaryl-CoA reductase EMBL BAH34206.1
EC=1.1.1.88 EMBL BAH34206.1

Gene names

Name:	mvaA EMBL BAH34206.1
Ordered Locus Names:	RER_34980

Organism

Rhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]

Taxonomic identifier

234621 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	429 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL BAH34206.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C1A0S1 [UniParc]. Last modified May 26, 2009. Version 1. Checksum: 0742D8D0D637EF5F	FASTA	429	44,932
	10 20 30 40 50 60 MSINSRSINS RIANFRSYDV AARRAEIVRQ TDLTEADIAV YDAADGLTID QADRMVENVV 70 80 90 100 110 120 GVIGIPVGVA TNFTINGTDY LIPLATEEPS VVAAASNAAR IARGLGGFHV SSTPPIMQAQ 130 140 150 160 170 180 IQLVDVVDPA AARIRLLEAR EEIIALANEQ DPKLVSVGGG VKDISVRIVP SDKATYVVLH 190 200 210 220 230 240 LHVDVRDAMG ANAVNTMAEA IADRVAEIGG GHVVLRILTN KADLRLTRVR AVFDAELIGG 250 260 270 280 290 300 AEVVDNLIHA ARLAELDPYR AATHNKGIMN GISAVVLATG NDTRAVEAGC HSHAVNADGI 310 320 330 340 350 360 YSSLSHFEKN ADGNIVGTLE LPMPVGLVGG ATKVHPVAQA AIKMLGVESA EELAGIILAV 370 380 390 400 410 420 GLAQNLAAVR VLASEGVQRG HMGLHARNIA ATAGAQKSEI DAVVARLIAD KSIRVEHAEK VLTEIRGGN

References

[1]

"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4." Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008957 Genomic DNA. Translation: BAH34206.1.
RefSeq	YP_002766945.1. NC_012490.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C1A0S1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7715047.
GenomeReviews	Gene locus RER_34980 in contig AP008957_GR.
KEGG	rer:RER_34980.
PATRIC	23193472. VBIRhoEry66701_4014.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NNKGIMN.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS00318. HMG_COA_REDUCTASE_2. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C1A0S1_RHOE4

Accession

Primary (citable) accession number: C1A0S1

Entry history

Integrated into UniProtKB/TrEMBL:	May 26, 2009
Last sequence update:	May 26, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)