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C0ZZC4 (C0ZZC4_RHOE4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Name:pyrC EMBL BAH33709.1
Ordered Locus Names:RER_30010
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
C0ZZC4 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: F6C9EC0B3ABCC52D

FASTA43545,953
        10         20         30         40         50         60 
MSVLLRGVLI YGEGEPTDVL VGDGTILEIG VDLDPATASE VIDAGGQILL PGFVDLHTHL 

        70         80         90        100        110        120 
REPGREDTET IETGSSAAAL GGYTAVFAMA NTSPVADSVV ITDHVWRRGQ EVGLVDVHPV 

       130        140        150        160        170        180 
GAVTAGLEGK QLAEMATMAA GVGKVKMFSD DGHCVYDPLI MRRALEYSSS LGVLIAQHAE 

       190        200        210        220        230        240 
EPRLTVGAVA HEGPTAARLG LAGWPRAAEE SIVARDALLA RDAGARVHIC HASTAGTVEL 

       250        260        270        280        290        300 
VKWARSQGIS ITAEVTPHHL LLDDSRLETY DAINKVNPPL REASDVAALR KGLAEGIIDC 

       310        320        330        340        350        360 
VATDHAPHAE QDKCCEFAAA RPGMLGLETA LSIIVQTMVQ PGLLDWRGVA RVMSERPAAI 

       370        380        390        400        410        420 
VGLDDQGRPI EVGEPANLTL VDPSAEWTVH GPDLASVAHN TPYESMTLPA RVTTTLLRGR 

       430 
ITAHDGNVRL RSSEE

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH33709.1.
RefSeqYP_002766448.1. NC_012490.1.

3D structure databases

ProteinModelPortalC0ZZC4.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZZC4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7712434.
GenomeReviewsGene locus RER_30010 in contig AP008957_GR.
KEGGrer:RER_30010.
PATRIC23192434. VBIRhoEry66701_3502.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMANTPYESM.
ProtClustDBPRK09357.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0ZZC4_RHOE4
AccessionPrimary (citable) accession number: C0ZZC4
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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