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C0ZZ60 (C0ZZ60_RHOE4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate dehydrogenase RuleBase RU000422
EC=1.1.1.37 RuleBase RU000422
Gene names
Name:mdh EMBL BAH33645.1
Ordered Locus Names:RER_29370
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. SAAS SAAS001252

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU000422 SAAS SAAS010945

Subunit structure

Homodimer By similarity. SAAS SAAS010945

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 2 family. RuleBase RU000421

Sequences

Sequence LengthMass (Da)Tools
C0ZZ60 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 0A26870AF5DD0321

FASTA32934,370
        10         20         30         40         50         60 
MSIAPVTVTV TGASGQIAYG MLFRIAAGEM LGADVPIKLR LLEIPAAVSA AEGVAMELED 

        70         80         90        100        110        120 
GAFPLLSSID ITDDPDVAFS GANVGMLVGA RPRSKGMERA DLLSANGAIF TAHGKAINNN 

       130        140        150        160        170        180 
AASDVKVLVV GNPANTNALI AMNNAPDVPD TRFSALTRLD HNRAIAQVVK KTGVRASSVR 

       190        200        210        220        230        240 
KVSVWGNHSA TQYPDLSHAT VAGEPALAVI NDRDWVENDF IPTVQVRGTA IIAARGSSSA 

       250        260        270        280        290        300 
ASAASASIDH VRDWVIGTAE DDWVSMAVCS DGSYGVPEGL ISSFPVTCAD GEFAIVPDLA 

       310        320 
IDDFSRERID LSVSELEQER AAVRELGFV

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH33645.1.
RefSeqYP_002766384.1. NC_012490.1.

3D structure databases

ProteinModelPortalC0ZZ60.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZZ60.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7709223.
GenomeReviewsGene locus RER_29370 in contig AP008957_GR.
KEGGrer:RER_29370.
PATRIC23192304. VBIRhoEry66701_3437.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMADPNVAFK.
ProtClustDBPRK05442.

Family and domain databases

HAMAPMF_01517. Malate_dehydrog_2.
[Tree]
InterProIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.90.110.10. lact_mal_DH. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00024.
PANTHERPTHR23382. MDH_SF1. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMSSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMsTIGR01759. MalateDH-SF1. 1 hit.
PROSITEPS00068. MDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0ZZ60_RHOE4
AccessionPrimary (citable) accession number: C0ZZ60
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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