Skip Header

Contribute Send feedback
Read comments (?) or add your own

C0ZX05 (AROA_RHOE4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:RER_21820
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4374373-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000204169

Sequences

Sequence LengthMass (Da)Tools
C0ZX05 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: 855BB964A55CDB45

FASTA43744,918
        10         20         30         40         50         60 
MDHVSLSLWS APRAQAPVDA VVTLPGSKSI TNRALILAAL ADGPSTITGA LRSRDADLMI 

        70         80         90        100        110        120 
AALRDLGIGV EEAGDPTTLR ITPGPLRGGE VDCGLAGTVM RFLPPLAAMA DGIVRFDGDE 

       130        140        150        160        170        180 
QARTRPLGTI LEALRGLGAR IEGDALPFTV TGTGSLRGGT VTIDASGSSQ FVSGLLLSAA 

       190        200        210        220        230        240 
AFEEGVTVHH DGKPVPSMPH IDMTVEMLRQ SGVSVTTPAT GGDADTWRVA PGPVRAVDWA 

       250        260        270        280        290        300 
IEPDLSNATP FLAAAAVTGG TVSVPMWPSS TTQPGDAIRG ILASMGADVT LADGVLTVRG 

       310        320        330        340        350        360 
PEKLRGIDID LHDVGELTPT VAALAALAEG TSHLRGIAHL RGHETDRLAA LADEINKLGG 

       370        380        390        400        410        420 
SVTETDDGLT IVPAELHGGQ WLSYADHRMA TAGAIIGLVV DGVDVDDVGT TAKTLPGFEN 

       430 
MWIDMLESSP ATPKASF

« Hide

References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH32890.1.
RefSeqYP_002765629.1. NC_012490.1.

3D structure databases

ProteinModelPortalC0ZX05.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZX05.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7714361.
GenomeReviewsGene locus RER_21820 in contig AP008957_GR.
KEGGrer:RER_21820.
PATRIC23190774. VBIRhoEry66701_2684.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAHRMATAG.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_RHOE4
AccessionPrimary (citable) accession number: C0ZX05
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 26, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents