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C0ZWR0 (C0ZWR0_RHOE4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase 1 HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase 1 HAMAP MF_00186
Glycerokinase 1 HAMAP MF_00186
Gene names
Name:glpK EMBL BAH32795.1
Synonyms:glpK1 HAMAP MF_00186
Ordered Locus Names:RER_20870
OrganismRhodococcus erythropolis (strain PR4 / NBRC 100887) [Complete proteome] [HAMAP]
Taxonomic identifier234621 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding409 – 4135ATP By similarity HAMAP MF_00186

Sites

Binding site121Substrate By similarity HAMAP MF_00186
Binding site161ATP By similarity HAMAP MF_00186
Binding site821Substrate By similarity HAMAP MF_00186
Binding site1341Substrate By similarity HAMAP MF_00186
Binding site2421Substrate By similarity HAMAP MF_00186
Binding site2641ATP By similarity HAMAP MF_00186
Binding site3081ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
C0ZWR0 [UniParc].

Last modified May 26, 2009. Version 1.
Checksum: EA64D918D43CA447

FASTA49653,910
        10         20         30         40         50         60 
MNQYIAAIDQ GTTSSRCMIF DHDGAVVSVA QKEHEQIFPR AGWVEHDPVA LWINTREVVA 

        70         80         90        100        110        120 
GALAKVDLTR ADIAAVGITN QRETTVVWER STGKPIYNAI VWQDTRTDQL CVELGGDEGP 

       130        140        150        160        170        180 
DKYRDKTGLP LSTYFAGPKI RWILDNVDGA RAKAEAGELC FGTVDTWIVW NLTDGVHVTD 

       190        200        210        220        230        240 
VTNASRTMLM DLETLQWDES ICADFGIPMS MLPEIRSSSE VYGTGRPRGN LAGVPVAGIL 

       250        260        270        280        290        300 
GDQQAATFGQ ACLSEGEAKN TYGTGNFMLL NTGTKPVHSK HGLLTTVCYK LGEAPAVYAL 

       310        320        330        340        350        360 
EGSVAVTGSL VQWLRDNLGI IQNAKDIEPL AASVDDNGGA YFVPAFSGLF APRWRPDARG 

       370        380        390        400        410        420 
VIVGLTRFVN KGHLARAALE ATAYQTREVI DAMRADSGVE LSALKVDGGM VVNETLMQFQ 

       430        440        450        460        470        480 
SDILGVPVIR PVVNETTALG AAYAAGLAIG YWADTEDIRN NWAVGQTWEP AMGESERSRL 

       490 
YAEWNKAVER TYNWSE

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References

[1]"Comparison of the complete genome sequences of Rhodococcus erythropolis PR4 and Rhodococcus opacus B4."
Takarada H., Sekine M., Hosoyama A., Yamada R., Fujisawa T., Omata S., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PR4 / NBRC 100887.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008957 Genomic DNA. Translation: BAH32795.1.
RefSeqYP_002765534.1. NC_012490.1.

3D structure databases

ProteinModelPortalC0ZWR0.
ModBaseSearch...

Protein-protein interaction databases

STRINGC0ZWR0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7714301.
GenomeReviewsGene locus RER_20870 in contig AP008957_GR.
KEGGrer:RER_20870.
PATRIC23190578. VBIRhoEry66701_2586.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACTDVSNA.
ProtClustDBCLSK726606.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC0ZWR0_RHOE4
AccessionPrimary (citable) accession number: C0ZWR0
Entry history
Integrated into UniProtKB/TrEMBL: May 26, 2009
Last sequence update: May 26, 2009
Last modified: December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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